CTR9
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Official Full Name
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -
Overview
CTR9, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and PAF1 (MIM 610506) form the PAF protein complex, which;associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex;(Rozenblatt-Rosen et al., 2005 (PubMed 15632063)). -
Synonyms
CTR9;Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae);SH2 domain binding protein 1 (tetratricopeptide repeat containing) , SH2BP1;RNA polymerase-associated protein CTR9 homolog;KIAA0155;p150TSP;TSBP;p150TSP.;Paf1/RNA polymerase II complex component homolog Ctr9;SH2 domain binding protein 1;SH2BP1;Ctr 9;Ctr9 Paf1/RNA polymerase II complex component, homolog;p150;RNA polymerase associated protein CTR9 homolog;SH2 binding phosphoprotein;SH2 domain binding protein 1 (tetratricopeptide repeat containing);TPR containing SH2 binding phosphoprotein;OTTHUMP00000230974;SH2 domain-binding protein 1;TPR-containing, SH2-binding phosphoprotein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CTR9-5434Z | Recombinant Zebrafish CTR9 | Mammalian Cell | Zebrafish | His |
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| CTR9-7195HCL | Recombinant Human CTR9 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
CTR9 involved in several pathways and played different roles in them. We selected most pathways CTR9 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CTR9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CTR9 has several biochemical functions, for example, RNA polymerase II core binding,SH2 domain binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTR9 itself. We selected most functions CTR9 had, and list some proteins which have the same functions with CTR9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core binding | ZFP326,CDC73,WACA,RECQL5,SMYD3,SMYD2A,AGO1,PCF11,GTF2E1,RPRD1B |
| protein binding | NOSIP,PCNA,DBNL,BEND5,LRR1,MIEN1,STX4A,SRGAP1,AMIGO2,CSDE1 |
| SH2 domain binding | LAT2,SRC,AFAP1L2,SYP,DLC1,SYNGR3,MS4A2,NLK,LAX1,DAG1 |
Interacting Protein
CTR9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTR9 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTR9.
CDC73;PAF1
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References
- Hanks, S; Perdeaux, ER; et al. Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour. NATURE COMMUNICATIONS 5:-(2014).
- Yoo, HS; Choi, Y; et al. Transcriptional Regulator CTR9 Inhibits Th17 Differentiation via Repression of IL-17 Expression. JOURNAL OF IMMUNOLOGY 192:1440-1448(2014).
