CTNNA3
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Official Full Name
catenin (cadherin-associated protein), alpha 3 -
Synonyms
CTNNA3;catenin (cadherin-associated protein), alpha 3;catenin alpha-3;MGC26194;VR22;4930429L08Rik;4933408A16;Alpha catenin like protein;Alpha T catenin;Alpha T-catenin;Cadherin associated protein;Cadherin-associated protein;Catenin alpha 3;Catna3;CTNA3_HUMAN;MGC75041;OTTHUMP00000019684;OTTMUSP00000028119;OTTMUSP00000028120;RP11-433J16.1;alpha-T-catenin;alpha-catenin-like protein
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CTNNA3 involved in several pathways and played different roles in them. We selected most pathways CTNNA3 participated on our site, such as Hippo signaling pathway,Adherens junction,Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTNNA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tight junction | RHOAB,MPP5A,SHROOM4,INADL,CASK,ACTN1,CRB3,VMHCL,SHROOM3,ASH1L |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ITGA3,ACTN2,LMNA,ATP2A2,DAG1,SLC8A1,RYR2,ACTN1,ITGA4,ITGB8 |
| Leukocyte transendothelial migration | RAC2,CLDN11,ITGB1,THY1,NIPAL1,CLDN23,GNAI3,PTK2B,CLDN17,MYL5 |
| Pathways in cancer | FGF18,XIAP,CKS2,Adcy4,FZD8,SOS1,FGF7,GRB2,CSF3R,PML |
| Endometrial cancer | MAPK1,PIK3CD,KRAS,MLH1,CASP9,TCF7L2,BRAF,SOS1,AXIN2,ILK |
| Adherens junction | RHOAD,PTPN1,ACTN3A,ACP1,RHOAA,RAC3A,WASF3B,Fert2,AASS,RHOA |
| Bacterial invasion of epithelial cells | ITGA5,CBL,CTNNA2,SRC,CTNNA1,SEPT9,PIK3R2,FN1,PIK3R3,SHC1 |
| Hippo signaling pathway | YWHAB,BMPR1B,BIRC2,AXIN1,PPP1CC,WNT7B,JUB,ITGB2L,LEF1,WNT3 |
Protein Function
CTNNA3 has several biochemical functions, for example, actin filament binding,beta-catenin binding,cadherin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTNNA3 itself. We selected most functions CTNNA3 had, and list some proteins which have the same functions with CTNNA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication | DSP,DSG2,DSC2,PKP2,JUP |
| beta-catenin binding | EP300,SLC9A3R2,MED12L,DACT2,CDH5,CHD8,FAM123B,C,AXIN1,PTPRJ |
| cadherin binding | OLFM4,P2RX4,CD2AP,CDH13,JUPA,CTNND1,CTNNB1,PTPRM,CTNNA1,GNA13A |
| actin filament binding | MYH9,ADD1,SYNE3,SCIN,CORO1B,MYL4,MYH9A,TMOD1,SHROOM2,MYH11A |
| protein binding | DSCC1,BCKDHB,DIAPH1,LYN,HMBOX1,NOTCH2,RPL15,UBE2D4,CRCP,TBPL1 |
Interacting Protein
CTNNA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTNNA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTNNA3.
gag;CTNNB1;EPS8
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