CRY2

  • Official Full Name

    cryptochrome 2 (photolyase-like)

  • Overview

    Cryptochromes (from the Greek κρυπτ? χρ?μα, hidden colour) are a class of blue light-sensitive flavoproteins found in plants and animals. Cryptochromes are involved in the circadian rhythms of plants and animals, and in the sensing of magnetic fields in a number of species. The name Cryptochrome was proposed as a pun combining the cryptic nature of the photoreceptor, and the cryptogamic organisms on which many blue light studies were carried out.

  • Synonyms

    CRY2;cryptochrome 2 (photolyase-like);cryptochrome-2;growth-inhibiting protein 37;HCRY2;PHLL2;FLJ10332;KIAA0658

Recombinant Proteins

  • Human
  • Rat
  • Chicken
  • Mouse
  • Arabidopsis thaliana
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • In Vitro Cell Free System
  • Insect Cell
  • HEK293T
  • Mamanlian cells
  • His
  • Myc&DDK
  • GST
  • Non
  • His&Fc&Avi
  • His&Myc
  • His&Myc&SUMO
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
CRY2-11597H Recombinant Human CRY2, His-tagged E.coli Human His 243-593a.a.
CRY2-1159H Recombinant Human CRY2, MYC/DDK-tagged HEK293 Human Myc&DDK
CRY2-1609R Recombinant Rat CRY2 Protein Mammalian Cell Rat His
CRY2-1923H Recombinant Human CRY2 Protein, GST-tagged Wheat Germ Human GST
CRY2-26941TH Recombinant Human CRY2 Wheat Germ Human Non 91 amino acids
CRY2-5817C Recombinant Chicken CRY2 Mammalian Cell Chicken His
CRY2-7268HCL Recombinant Human CRY2 293 Cell Lysate HEK293 Human Non
CRY2-1267R Recombinant Rat CRY2 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
CRY2-1267R-B Recombinant Rat CRY2 Protein Pre-coupled Magnetic Beads HEK293 Rat
CRY2-2126HF Recombinant Full Length Human CRY2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 593 amino acids
CRY2-2308H Recombinant Human CRY2 protein, His&Myc-tagged Insect Cell Human His&Myc 1-593aa
Cry2-2324M Recombinant Mouse Cry2 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
CRY2-2390R Recombinant Rat CRY2 Protein (1-594 aa), His-SUMO-Myc-tagged E.coli Rat His&Myc&SUMO 1-594 aa
CRY2-5336HFL Recombinant Full Length Human CRY2, Flag-tagged Mamanlian cells Human Flag Full L.
CRY2-5566A Recombinant Mouse-ear cress CRY2 Protein (Met1-Lys612), N-His tagged E.coli Arabidopsis thaliana His Met1-Lys612
Cry2-5633M Recombinant Mouse Cry2 protein, His&Myc-tagged E.coli Mouse His&Myc 1-592a.a.
CRY2-647H Recombinant Human CRY2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK

    Involved Pathway

    CRY2 involved in several pathways and played different roles in them. We selected most pathways CRY2 participated on our site, such as BMAL1:CLOCK,NPAS2 activates circadian gene expression,Circadian Clock,Circadian rhythm, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRY2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Circadian Clock RAI1,DBP,NAMPT,HELZ2,CSNK1E,CRY1,CARM1,NRIP1,CPT1A
    BMAL1:CLOCK,NPAS2 activates circadian gene expression NRIP1,NCOA2,DBP,NAMPT,HELZ2,CRY1,CREBBP,CARM1
    Circadian rhythm PRKAA2,ARNTL,NR1D1,BHLHE40,CRY1,FBXL3,RORC,FBXW11,RORA,PRKAB1
    Diurnally regulated genes with circadian orthologs KLF9,CBX3,STBD1,NR1D2,G0S2,PURA,RBPMS,CRY1,EIF4G2,AZIN1

    Protein Function

    CRY2 has several biochemical functions, for example, NOT DNA (6-4) photolyase activity,DNA binding,FAD binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRY2 itself. We selected most functions CRY2 had, and list some proteins which have the same functions with CRY2. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor activity, transcription factor binding TP63,ASCL1B,CRY1,PER1,PER2,NEUROG1,LDB2A,ASCL1,TRP63,LDB1A
    protein binding ENOX1,HPN,KHDC1A,ZNF624,S100A2,C6orf130,COMT,FAM118B,ZNF567,DSTN
    phosphatase binding PPARA,TPRN,SPRED1,MAGI2,CSRNP2,MAST2,PPP1R18,DLG3,SLC9A3R2,KLRAQ1
    blue light photoreceptor activity CRY1
    single-stranded DNA binding BLM,HMGB1,TDP2B,PURB,NME2,ALYREF,ERCC5,OBFC2B,MCM10,NABP1A
    damaged DNA binding NEIL3,ERCC3,H2AFX,CRY-DASH,MGMT,RAD18,XPC,RBBP8,TRP53,XPA
    transcription regulatory region sequence-specific DNA binding EGR1,CREB3L3,POU5F1,NKX3-1,POU2F1,NFE2L1,PER2,NR5A1B,NR5A1,SFPQ
    DNA binding ZNF576,SPZ1,ZFP687,PROX1A,FOXD1L,ZFP879,LHX6,HIST2H4A,CBFB,ZFP689
    ubiquitin binding NSFL1C,UCHL1,KIF18A,DYRK2,PER2,FAN1,TRP53INP2,UCHL3,C6orf106,C36E6.2

    Interacting Protein

    CRY2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRY2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRY2.

    PDE9A;CTBP1;MTUS2;Csnk1e;TIMELESS;ATXN1;STK11;CSNK1E;PER3

    Resources

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