CRHBP
-
Official Full Name
corticotropin releasing hormone binding protein -
Overview
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. -
Synonyms
CRHBP;corticotropin releasing hormone binding protein;corticotropin-releasing factor-binding protein;CRF BP;CRFBP;CRF binding protein;CRH BP;Corticotropin releasing factor binding protein;CRH-BP;CRF-binding protein;corticotropin releasing hormone-binding protein;corticotropin-releasing hormone-binding protein;CRF-BP
Recombinant Proteins
- Rhesus macaque
- Human
- Zebrafish
- Mouse
- Rat
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&GST
- His&Fc&Avi
- Flag
Involved Pathway
CRHBP involved in several pathways and played different roles in them. We selected most pathways CRHBP participated on our site, such as Corticotropin-releasing hormone, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRHBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Corticotropin-releasing hormone | IVL,JUNB,CRH,CASP12,TCF4,TBX19,CYP11A1,PARP1,CYP11B1,TRIM28 |
Protein Function
CRHBP has several biochemical functions, for example, corticotropin-releasing hormone binding,peptide binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRHBP itself. We selected most functions CRHBP had, and list some proteins which have the same functions with CRHBP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| corticotropin-releasing hormone binding | CRHR1 |
| peptide binding | GNRHR2,GPR22,ENPEP,CLTB,PPIB,OXTR,TPP1,NUP98,FNTB,H2-Q10 |
| protein binding | IARS,CCDC137,EIF6,NUP37,CNO,PARVA,STRADB,SIK2,VAMP7,NOP58 |
Interacting Protein
CRHBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRHBP here. Most of them are supplied by our site. Hope this information will be useful for your research of CRHBP.
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