CPNE6

  • Official Full Name

    copine VI (neuronal)

  • Overview

    This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.

  • Synonyms

    CPNE6;copine VI (neuronal);copine-6;Copine 6;Copine VI;Copine6;CopineVI;CPNE6_HUMAN;N copine;N-copine;Neuronal copine;Neuronal-copine;OTTHUMP00000027965

Recombinant Proteins

  • Human
  • Mouse
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • Flag
  • Avi
  • Fc
  • DDK
  • Myc

    Involved Pathway

    CPNE6 involved in several pathways and played different roles in them. We selected most pathways CPNE6 participated on our site, such as Glycerophospholipid biosynthesis,Metabolism,Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPNE6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism HS3ST6,PHOSPHO1,COX6C,CYP2A7,CDIPT,TCN1,OAZ2,KCNC2,COX7C,SULT1B1
    Metabolism of lipids and lipoproteins ARSJ,AKR1C21,SLC27A2A,MED23,FA2H,CYP27A1,CYP4B1,ARSK,DGAT1B,GC
    Glycerophospholipid biosynthesis CHKA,GPAT2,PLB1,DGAT1B,PLBD1,MGLL,PEMT,AGPAT1,CDIPT,ABHD4
    Phospholipid metabolism PHOSPHO1,CHKB,DGAT1B,CEPT1,CEPT1A,ARF3,AWAT2,FIG4,CPNE7,PLD6

    Protein Function

    CPNE6 has several biochemical functions, for example, calcium ion binding,phosphatidylserine binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPNE6 itself. We selected most functions CPNE6 had, and list some proteins which have the same functions with CPNE6. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding CAPSLA,MATN3A,SDF4,C1S,RAB11FIP4,NOTCH2NL,PCDHGC3,MMP14B,ITSN2A,THBS4
    phosphatidylserine binding FCHO2,SCIN,CD300A,AP1S2,JPH2,AXL,RS1,SDPR,THBS1,MFGE8
    transporter activity SLCO1B2,SLC5A6A,SYPL,SV2C,RLBP1A,AQP11,ATP5J,OSTA,AQP1A.1,LCN5
    protein binding HIF1A,SIGIRR,EPHB1,KIF20B,KRTAP4-2,LSM8,OCRL,TRIM42,SLC48A1,BCL10

    Interacting Protein

    CPNE6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPNE6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPNE6.

    MEOX2;TTR;TK1;ANXA7;CDKN1A;PIN1;GRB7;MAPK11;SMN1;LAMTOR3;AK5

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