Cort
-
Official Full Name
Corticosterone -
Overview
Corticosterone is a steroid hormone secreted by the outer layer, or cortex, of the adrenal gland . Classed as a glucocorticoid, corticosterone helps regulate the conversion of amino acids into carbohydrates and glycogen by the liver, and helps stimulate glycogen formation in the tissues. Corticosterone is similar in structure, although somewhat less potent, than the other glucocorticoids cortisol and cortisone . It is produced in response to stimulation by the pituitary substance adrenocorticotropic hormone (ACTH). In some species, but not in humans, corticosterone is the predominant glucocorticoid secreted by the adrenal. It is a precursor in the synthesis of aldosterone , another adrenal cortical steroid. -
Synonyms
CORT;Corticosterone;CST;PCST
Recombinant Proteins
- Rat
- Human
- Mouse
- Pan-species
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
Cort involved in several pathways and played different roles in them. We selected most pathways Cort participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Cort were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Cort has several biochemical functions, for example, G-protein coupled receptor binding,neuropeptide hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cort itself. We selected most functions Cort had, and list some proteins which have the same functions with Cort. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor binding | GNAL,GNAT2,PSAPL1,PICK1,PACRG,INSL3,RSPO2,ITGB4,POMC,ADORA1 |
| neuropeptide hormone activity | NPFF,ADCYAP1,HCRT,NPY,C12orf39,PENK,AVP,NPFFL,QRFP,UCN |
Interacting Protein
Cort has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cort here. Most of them are supplied by our site. Hope this information will be useful for your research of Cort.
Resources
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References
- Schmidt, KL; Kubli, SP; et al. Early-Life Stress Has Sex-Specific Effects on Immune Function in Adult Song Sparrows. PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY 88:183-194(2015).
- Kankova, Z; Okuliarova, M; et al. Immune responsiveness of Japanese quail selected for egg yolk testosterone content under severe protein restriction. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY 177:41-48(2014).
