COL9A3
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Official Full Name
collagen, type IX, alpha 3 -
Overview
This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. Mutations in this gene are associated with multiple epiphyseal dysplasia type 3. -
Synonyms
COL9A3;collagen, type IX, alpha 3;collagen alpha-3(IX) chain;collagen type IX proteoglycan;DJ885L7.4.1;EDM3;FLJ90759;IDD;MED;alpha 3 type IX collagen;collagen IX alpha-3 polypeptide;collagen type IXalpha 3;OTTHUMP00000031507;collagen IX, alpha-3 polypeptide
Recombinant Proteins
- Human
- Chicken
- Mouse
- Wheat Germ
- Mammalian Cells
- HEK293
- GST
- His
- Non
- DDK
- Myc
- Flag
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| COL9A3-1665H | Recombinant Human COL9A3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| COL9A3-6857C | Recombinant Chicken COL9A3 | Mammalian Cells | Chicken | His |
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| COL9A3-7374HCL | Recombinant Human COL9A3 293 Cell Lysate | HEK293 | Human | Non |
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| COL9A3-1680H | Recombinant Human COL9A3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| COL9A3-2143HFL | Recombinant Full Length Human COL9A3 Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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| COL9A3-640H | Recombinant Human COL9A3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| COL9A3-640H-B | Recombinant Human COL9A3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| Col9a3-920M | Recombinant Mouse Col9a3 Protein, MYC/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
COL9A3 involved in several pathways and played different roles in them. We selected most pathways COL9A3 participated on our site, such as Axon guidance,Collagen biosynthesis and modifying enzymes,Collagen degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL9A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | CLTA,EPHB3A,DOCK1,KDR,NTN1A,RHOB,RNF8,EPHB4A,AP2A2,AP2B1 |
| ECM proteoglycans | ASPN,ACAN,MUSK,COMP,VCANB,PTPRS,BGNB,MATN4,FMOD,MATN3 |
| Collagen biosynthesis and modifying enzymes | COL28A1D,LEPREL1,SERPINH1A,LEPREL2,COL1A1,COL9A1B,COL28A1A,LEPRE1,COL16A1,P3H2 |
| Collagen formation | COL13A1,EMID2,PCOLCEA,COL19A1,COL5A2,CRTAP,TLL2,BMP1B,DST,COL6A2 |
| Collagen degradation | MMP19,COL17A1,MMP11,TLDC2,CTSK,MMP8,CTS7,MMP10,COL25A1,COL15A1B |
| Extracellular matrix organization | HAPLN1,SERPINH1B,CTSLL,TIMP2,COL15A1B,P3H2,TLL1,MUSK,LOXL3,FBLN2 |
| Axon guidance | SEMA3D,CNTN1,SEMA3AA,ROBO3,RHOGA,Sema3f,RGS3,DLG3,CLTB,TRIO |
| Degradation of the extracellular matrix | MMP10,BSG,CAPNS1,ADAM15,ADAMTS8,ADAMTS4,COL17A1,MMP19,MMP12,MMP17 |
Protein Function
COL9A3 has several biochemical functions, for example, extracellular matrix structural constituent conferring tensile strength. Some of the functions are cooperated with other proteins, some of the functions could acted by COL9A3 itself. We selected most functions COL9A3 had, and list some proteins which have the same functions with COL9A3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| extracellular matrix structural constituent conferring tensile strength | COL2A1,COL9A1 |
Interacting Protein
COL9A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL9A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL9A3.
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