CNGA2
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Official Full Name
cyclic nucleotide gated channel alpha 2 -
Overview
The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. -
Synonyms
CNGA2;cyclic nucleotide gated channel alpha 2;CNCA, CNCA1;cyclic nucleotide-gated olfactory channel;CNG2;FLJ46312;OCNC1;OCNCa;OCNCalpha;CNG-2;CNG channel alpha-2;cyclic nucleotide-gated channel alpha-2;cyclic nucleotide-gated cation
Recombinant Proteins
- Human
- Rat
- Mouse
- Mus musculus
- Oryctolagus cuniculus (Rabbit)
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
CNGA2 involved in several pathways and played different roles in them. We selected most pathways CNGA2 participated on our site, such as Assembly of the primary cilium,Cargo trafficking to the periciliary membrane,Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CNGA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| VxPx cargo-targeting to cilium | RAB3IP,ARF4A,PKD1,PKD2,CNGA5,ARF4 |
| cAMP signaling pathway | HTR1B,PTCH1,PPP1R12A,MAP2K1,BAD,HTR1F,RELA,ATP1B2,SUCNR1,ATP2A2 |
| Cargo trafficking to the periciliary membrane | PKD1,SETD6,ARF4,EXOC1,EXOC3,EXOC5,EXOC8,RP2,ARF4A,BBS2 |
| Organelle biogenesis and maintenance | WDR35,CC2D2A,EXOC6,MARK4,MRPL28,POLG2,GFM2,MTERF,CNGA5,MTFMT |
| Assembly of the primary cilium | DYNLL2A,MAPRE1,HDAC6,SDCCAG8,KIF3CB,B9D2,TCP1,OFD1,CSNK1D,PROL1 |
Protein Function
CNGA2 has several biochemical functions, for example, cAMP binding,cGMP binding,calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CNGA2 itself. We selected most functions CNGA2 had, and list some proteins which have the same functions with CNGA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| voltage-gated potassium channel activity | HTR3A,KCNC1A,KCNMA1,KCNQ2A,KCNE4,KCNK5,KCNJ11,KCNC3B,KCNQ5,KCNV2 |
| intracellular cGMP activated cation channel activity | CNGA3,CNGA4,AQP1,CNGA5,CNGA1 |
| cAMP binding | PRKAR2B,CNGA4,PDE4B,PRKAR1A,BVES,PDE11A,PDE2A,PDE4A,RAPGEF3,PRKAR2A |
| calmodulin binding | INVS,PCP4,SCN5A,MYO5C,CNN3,PDE1A,SLC8A1,PHKG1B,ITPKC,NETO2 |
| cGMP binding | CNGA3,PDE10A,PDE6G,PRKG1A,PDE2A,PDE5A,CNGA4,PDE11A,PRKG1,PRKG2 |
Interacting Protein
CNGA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNGA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CNGA2.
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