CLEC9A
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Official Full Name
C-type lectin domain family 9, member A -
Overview
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008] -
Synonyms
CLEC9A;C-type lectin domain family 9, member A;DNGR1;UNQ9341;C-type lectin domain family 9 member A;HEEE9341
Recombinant Proteins
- Mouse
- Human
- Rat
- Rhesus macaque
- CHO
- HEK293
- Mammalian Cell
- Wheat Germ
- Mouse myeloma cell line
- E.coli
- In Vitro Cell Free System
- E.coli expression system
- Fc
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
CLEC9A involved in several pathways and played different roles in them. We selected most pathways CLEC9A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC9A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
CLEC9A has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC9A itself. We selected most functions CLEC9A had, and list some proteins which have the same functions with CLEC9A. You can find most of the proteins on our site.
Function | Related Protein |
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carbohydrate binding | GFPT1,CLEC14A,CD207,CD55,LGALS2,CD93,CLEC3A,GANC,GALNT5,LMAN2 |
Interacting Protein
CLEC9A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC9A here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC9A.
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References
- Picco, G; Beatson, R; et al. Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas. EUROPEAN JOURNAL OF IMMUNOLOGY 44:1947-1955(2014).
- Hartung, E; Becker, M; et al. Induction of Potent CD8 T Cell Cytotoxicity by Specific Targeting of Antigen to Cross-Presenting Dendritic Cells In Vivo via Murine or Human XCR1. JOURNAL OF IMMUNOLOGY 194:1069-1079(2015).