CLEC12A

  • Official Full Name

    C-type lectin domain family 12, member A
  • Overview

    CLEC12A, also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family. Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylat
  • Synonyms

    CLEC12A;C-type lectin domain family 12, member A;C-type lectin domain family 12 member A;CLL 1;MICL;C-type lectin superfamily;C-type lectin protein CLL-1;C-type lectin-like molecule-1;dendritic cell-associated lectin 2;myeloid inhibitory C-type lectin-like receptor;CLL1;CLL-1;DCAL-2;MGC70602

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • Cynomolgus
  • HEK293
  • CHO
  • Wheat Germ
  • Human Cell
  • In Vitro Cell Free System
  • E.coli
  • Insect Cell
  • His
  • Fc
  • Fc&Avi
  • N-His,C-Avi
  • Non
  • GST
  • His&Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CLEC12A-4689H Active Recombinant Human CLEC12A Protein, His-tagged, Site-specific PE-Labeled HEK293 Human His His 65 - Ala 265
CLEC12A-20H Active Recombinant Human CLEC12A Protein (Thr67-Ala265), N-hFc tagged CHO Human Fc Thr67-Ala265
CLEC12A-213H Active Recombinant Human CLEC12A Protein, hFc-tagged HEK293 Human Fc His65-Ala265
CLEC12A-2947H Active Recombinant Human CLEC12A protein, Fc-Avi-tagged, Biotinylated HEK293 Human Fc&Avi His 65-Ala 265
CLEC12A-2948H Recombinant Human CLEC12A protein, His,Avi-tagged, Biotinylated HEK293 Human N-His,C-Avi His65-Ala265
CLEC12A-2950H Active Recombinant Human CLEC12A protein, Fc-tagged HEK293 Human Fc His 65-Ala 265
CLEC12A-1455H Recombinant Human CLEC12A Protein Wheat Germ Human Non
CLEC12A-1456H Recombinant Human CLEC12A Protein, GST-tagged Wheat Germ Human GST 108-221 a.a.
CLEC12A-3547M Recombinant Mouse CLEC12A Protein, His-tagged HEK293 Mouse His
CLEC12A-6910H Recombinant Human CLEC12A protein(His75-Ala275), His-tagged HEK293 Human His 75-275 a.a.
CLEC12A-1920HCL Recombinant Human CLEC12A cell lysate Human Cell Human Non
CLEC12A-01M Recombinant Rat CLEC12A Protein, His-tagged HEK293 Rat His
CLEC12A-102R Recombinant Rat CLEC12A Protein, His-tagged HEK293 Rat His
CLEC12A-1908C Recombinant Cynomolgus CLEC12A protein, His-tagged HEK293 Cynomolgus His His 65 - Ala 265
CLEC12A-1910C Recombinant Cynomolgus CLEC12A protein, His-tagged HEK293 Cynomolgus His His 32 - Ala 232
CLEC12A-193H Recombinant Human CLEC12A protein, His-tagged HEK293 Human His His65-Ala265
CLEC12A-2115HF Recombinant Full Length Human CLEC12A Protein In Vitro Cell Free System Human Full L. 265 amino acids
CLEC12A-2641M Recombinant Mouse CLEC12A Protein (65-267 aa), His-Myc-tagged E.coli Mouse His&Myc 65-267 aa
CLEC12A-2757M Recombinant Mouse CLEC12A Protein (65-267 aa), His-Myc-tagged Insect Cell Mouse His&Myc 65-267 aa
CLEC12A-2945R Recombinant Rat CLEC12A protein, His-tagged HEK293 Rat His Tyr 65-Leu 269
CLEC12A-2946M Recombinant Mouse CLEC12A protein, His-tagged HEK293 Mouse His Tyr 65 - Arg 267
CLEC12A-2949H Active Recombinant Human CLEC12A protein, His-tagged, FITC-Labeled HEK293 Human His His 65-Ala 265
CLEC12A-356R Recombinant Rat CLEC12A Protein, His-tagged HEK293 Rat His
CLEC12A-4691H Active Recombinant Human CLEC12A Protein, His-tagged, Site-specific APC-Labeled HEK293 Human His His 65 - Ala 265
CLEC12A-50H Active Recombinant Human CLEC12A Protein (Thr67-Ala265), N-hFc tagged CHO Human Fc Thr67-Ala265
CLEC12A-6910HF Recombinant Human CLEC12A Protein (His75-Ala275), N-His tagged, FITC Labeled Human Cell Human His His75-Ala275
CLEC12A-6910HFL Recombinant Full Length Human CLEC12A Protein, N-His-tagged Human Cell Human His Full L. 221aa
CLEC12A-74M Recombinant Mouse CLEC12A Protein, His-tagged HEK293 Mouse His

    Involved Pathway

    CLEC12A involved in several pathways and played different roles in them. We selected most pathways CLEC12A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC12A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    CLEC12A has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC12A itself. We selected most functions CLEC12A had, and list some proteins which have the same functions with CLEC12A. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding NOMO3,ATRNL1,REG1A,CLEC2G,PKD1L3,ZG16,G6PDX,REG1B,REG3G,CLEC18B

    Interacting Protein

    CLEC12A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC12A here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC12A.

    Resources

    References

    • Hangalapura, BN; van Loo, PF; et al. A NOVEL CLEC12AXCD3 BISPECIFIC ANTIBODY EFFICIENTLY INDUCES T-CELL MEDIATED LYSIS OF CLEC12A+AML BLASTS. HAEMATOLOGICA 99:294-294(2014).
    • Gagne, V; Marois, L; et al. Modulation of monosodium urate crystal-induced responses in neutrophils by the myeloid inhibitory C-type lectin-like receptor: potential therapeutic implications. ARTHRITIS RESEARCH & THERAPY 15:-(2013).

    Reviews

    Reviews
    06/06/2024

    The effect of immunizing mice with this protein is very good.

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