CLDN7
-
Official Full Name
claudin 7 -
Overview
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010] -
Synonyms
CLDN7;claudin 7;CLDN-7;CEPTRL2;CPETRL2;Hs.84359;claudin-1;claudin-7;clostridium perfringens enterotoxin receptor-like 2
Recombinant Proteins
- Human
- Mouse
- Bovine
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- GST
- Non
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CLDN7-11299H | Recombinant Human CLDN7, GST-tagged | E.coli | Human | GST | 6-210a.a. | |
| CLDN7-1446H | Recombinant Human CLDN7 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| CLDN7-27069TH | Recombinant Human CLDN7 | Wheat Germ | Human | Non | 51 amino acids |
|
| CLDN7-3541M | Recombinant Mouse CLDN7 Protein | Mammalian Cells | Mouse | His |
|
|
| CLDN7-7459HCL | Recombinant Human CLDN7 293 Cell Lysate | HEK293 | Human | Non |
|
|
| CLDN7-028H | Recombinant Human CLDN7 Full Length Transmembrane protein(Nanodisc) | HEK293 | Human | Non | Full L. |
|
| CLDN7-1735M | Recombinant Mouse CLDN7 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| CLDN7-1735M-B | Recombinant Mouse CLDN7 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| CLDN7-2062HF | Recombinant Full Length Human CLDN7 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 211 amino acids |
|
| RFL1525HF | Recombinant Full Length Human Claudin-7(Cldn7) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-211) |
|
| RFL23007BF | Recombinant Full Length Bovine Claudin-7(Cldn7) Protein, His-Tagged | E.coli | Bovine | His | Full L. Full Length (1-211) |
|
Involved Pathway
CLDN7 involved in several pathways and played different roles in them. We selected most pathways CLDN7 participated on our site, such as Cell adhesion molecules (CAMs),Cell junction organization,Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hepatitis C | TLR3,NFKB1,MAPK12,PIAS1,NFKBIA,RNASEL,IRF3,CLDN18,Ifna11,IRF1 |
| Cell junction organization | PVRL2L,CDH6,CLDN4,LIMS1,PVRL1A,PLECA,CDH12,CDH3,TESK1,CD151 |
| Tight junction | MAGI1B,CLDN10,MYH3,JAM2,ACTB2,CASKB,CLDNJ,HRASA,CLDNE,MYH1C |
| Cell-Cell communication | CDH8,CLDN4,JUPA,ANG,CDH11,COL17A1A,RSU1,CADM2B,CDH18A,CDH12 |
| Leukocyte transendothelial migration | NIPAL1,CXCR4,VAV1,RASSF5,JAM3,MAPK11,PIK3CD,RHOA,MYL2,CLDN3 |
| Cell adhesion molecules (CAMs) | CDH15,ITGA6,NEGR1,CD80,MHC2DEB,ITGB1,CLDNB,PTPRF,HLA-F,HLA-DMA |
| Tight junction interactions | CLDN4,CLDN20,CLDN3,CLDN16,INADL,CLDN23 |
| Cell-cell junction organization | CDH4,CLDN23,CDH12,CDH10,CDH24,CDH12A,CDH18,CDH3,CLDN16,CLDN4 |
Protein Function
CLDN7 has several biochemical functions, for example, identical protein binding,protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN7 itself. We selected most functions CLDN7 had, and list some proteins which have the same functions with CLDN7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | HSPB1,NOL3,SEPT7,C1QTNF9,TRP53,CUBN,DIAPH1,EWSR1,TARDBP,SLK |
| protein binding | HIRIP3,KLHDC3,PFDN5,ZCCHC7,EIF2B1,MTDH,CNNM3,SEMG1,RASSF1,SH3RF1 |
| structural molecule activity | NCR3LG1,CLDN18,KRT34,EPB41L3B,CLTB,SEPT4,LMNA,TUBB,EVPLA,CDC42SE1 |
Interacting Protein
CLDN7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN7.
SYNE4;TACSTD2;HGD;RHOXF2
Resources
Related Services
Related Products
References
