CKAP4
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Official Full Name
cytoskeleton-associated protein 4 -
Overview
Cytoskeleton-associated protein 4 is a protein that in humans is encoded by the CKAP4 gene. -
Synonyms
CKAP4;cytoskeleton-associated protein 4;CLIMP 63;ERGIC 63;P63;63 kDa membrane protein;type-II transmembrane protein p63;63-kDa cytoskeleton-linking membrane protein;transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- C-His
- HEK293
- Insect Cells
- GST
- His
- His&Fc&Avi
- His&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CKAP4-11261H | Recombinant Human CKAP4, GST-tagged | E.coli | Human | GST | 254-602a.a. | |
| CKAP4-28002TH | Recombinant Human CKAP4 protein, His-tagged | E.coli | Human | His | 254-602 aa | |
| CKAP4-3492M | Recombinant Mouse CKAP4 Protein | Mammalian Cells | Mouse | His |
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| CKAP4-001H | Recombinant Human CKAP4 protein, His-tagged | C-His | Human | 128-602 aa |
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| CKAP4-1705M | Recombinant Mouse CKAP4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CKAP4-1705M-B | Recombinant Mouse CKAP4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CKAP4-2484M | Recombinant Mouse CKAP4 Protein (109-575 aa), His-Myc-tagged | E.coli | Mouse | His&Myc | 109-575 aa |
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| CKAP4-2819M | Recombinant Mouse CKAP4 Protein (109-575 aa), His-MBP-tagged | Insect Cells | Mouse | His&Myc | 109-575 aa |
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| CKAP4-2831H | Recombinant Human CKAP4 protein(141-460 aa), C-His-tagged | E.coli | Human | His | 141-460 aa |
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| CKAP4-790H | Recombinant Human CKAP4 Protein, His-tagged | E.coli | Human | His | His128-Val602 |
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Involved Pathway
CKAP4 involved in several pathways and played different roles in them. We selected most pathways CKAP4 participated on our site, such as Metabolism of proteins,Protein processing in endoplasmic reticulum,Surfactant metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CKAP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | HSP90AA1.2,EIF2AK1,CAPN1,PKZ,SEC61A1,RRBP1A,UBE2E1,NFE2L2,PDIP5,SSR3 |
| Surfactant metabolism | ZDHHC2,CTSH,SLC34A2A,GPR116,CCDC59,SFTPBB,LMCD1,DMBT1,GATA6,SFTPC |
| Metabolism of proteins | PFDN4,SAMM50,EEF1G,DPAGT1,MGAT4B,SPON1B,EIF5A2,TIMM10,O3far1,IGFBP1A |
Protein Function
CKAP4 has several biochemical functions, for example, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CKAP4 itself. We selected most functions CKAP4 had, and list some proteins which have the same functions with CKAP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | PRPF6,GNL3,DHX37,MBNL2,UTP14A,EIF4G3,DSP,BTF3,RAVER1,UBC |
Interacting Protein
CKAP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CKAP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CKAP4.
env;env;USP50;NDUFB7;ATF4;MLH1;HAMP;MVP;THOC7;TSNAX;ASCC2;CCDC53;15-deoxy-delta(12,14;midostaurin
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References
- Barbier, M; Martinez-Ramos, I; et al. Surfactant Protein A Blocks Recognition of Pseudomonas aeruginosa by CKAP4/P63 on Airway Epithelial Cells. JOURNAL OF INFECTIOUS DISEASES 206:1753-1762(2012).
- Kazi, AS; Tao, JQ; et al. Role of the PI3-kinase signaling pathway in trafficking of the surfactant protein A receptor P63 (CKAP4) on type II pneumocytes. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 299:L794-L807(2010).
