CISD2
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Official Full Name
CISD2 CDGSH iron sulfur domain 2 [ Homo sapiens ] -
Overview
The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. -
Synonyms
1500009M05Rik;1500026J14Rik;1500031D15Rik;AI848398;B630006A20Rik;CDGSH iron sulfur domain 2;CDGSH iron-sulfur domain-containing protein 2;CDGSH type domain 2;CISD2;CISD2_HUMAN;Endoplasmic reticulum intermembrane small protein;ERIS;Miner1;MitoNEET related 1;MitoNEET-related 1 protein;NAF-1;Noxp70;Nutrient deprivation autophagy factor 1;Nutrient-deprivation autophagy factor-1;OTTHUMP00000219576;RGD1566242;WFS2;Zcd2;Zinc finger;Zinc finger, CDGSH type domain 2
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CISD2-11254H | Recombinant Human CISD2, His-tagged | E.coli | Human | His | 61-135a.a. | |
| CISD2-10698Z | Recombinant Zebrafish CISD2 | Mammalian Cells | Zebrafish | His |
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| CISD2-1379H | Recombinant Human CISD2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CISD2-3482M | Recombinant Mouse CISD2 Protein | Mammalian Cells | Mouse | His |
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| CISD2-7489HCL | Recombinant Human CISD2 293 Cell Lysate | HEK293 | Human | Non |
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| CISD2-1698M | Recombinant Mouse CISD2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CISD2-1698M-B | Recombinant Mouse CISD2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CISD2-1855HF | Recombinant Full Length Human CISD2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 135 amino acids |
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| CISD2-301649H | Recombinant Human CISD2 protein, GST-tagged | E.coli | Human | GST | Pro61-Val135 |
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| RFL33223LF | Recombinant Full Length Lithobates Catesbeiana Cdgsh Iron-Sulfur Domain-Containing Protein 2(Cisd2) Protein, His-Tagged | E.coli | Lithobates catesbeiana (American bullfrog) (Rana catesbeiana) | His | Full L. Full Length (1-135) |
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Involved Pathway
CISD2 involved in several pathways and played different roles in them. We selected most pathways CISD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CISD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CISD2 has several biochemical functions, for example, 2 iron, 2 sulfur cluster binding,metal ion binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CISD2 itself. We selected most functions CISD2 had, and list some proteins which have the same functions with CISD2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | TFAP2B,LRP4,UBE4A,RRAGA,SLC9A7,CIDEA,FGFR1OP,ACOT7,IZUMO3,DSCAML1 |
| protein binding | EGLN1,CNOT10,BCL2,IGF2BP3,CACNA1SB,RBM22,INTS5,AIMP2,BRCC3,STX12 |
| poly(A) RNA binding | HNRPLL,MEX3C,XRN1,SUGP2,PARP12,LARP4,NUPL2,C1orf53,GNL2,FAM46A |
| metal ion binding | RNFT1,ZSCAN1,ZIC2,SCRT1,SAP30,ZRANB1B,ZFP354B,MOB2,CYB561D2,ZNFL1 |
| 2 iron, 2 sulfur cluster binding | SDHB,FECH,AOX3,CISD1,ISCA2,ISCUB,GLRX5,AIFM3,UQCRFS1,FXN |
Interacting Protein
CISD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CISD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CISD2.
GH1;IKBKE;pi3p
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