CHSY1

  • Official Full Name

    chondroitin sulfate synthase 1

  • Overview

    CHSY1 synthesizes chondroitin sulfate, a glycosaminoglycan expressed on the surface of most cells and in extracellular matrices. Glycosaminoglycan chains are covalently linked to a wide range of core protein families and regulate many biologic processes, including cell proliferation and recognition, extracellular matrix deposition, and morphogenesis.

  • Synonyms

    CHSY1;chondroitin sulfate synthase 1;Chondroitin glucuronyltransferase 1;Chondroitin synthase 1;CHSS1_HUMAN;ChSy-1;Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1;N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1;N-acetylgalactosaminyltransferase 1;OTTHUMP00000194839;N-acetylgalactosaminyltransferase II;chondroitin glucuronyltransferase II;CHSY;CSS1;TPBS

Recombinant Proteins

  • Human
  • Zebrafish
  • Mouse
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • GST
  • His
  • His&Fc&Avi
  • His&GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
CHSY1-11235H Recombinant Human CHSY1, GST-tagged E.coli Human GST 449-802a.a.
CHSY1-11954Z Recombinant Zebrafish CHSY1 Mammalian Cell Zebrafish His
CHSY1-1348H Recombinant Human CHSY1 Protein, GST-tagged Wheat Germ Human GST
CHSY1-3458M Recombinant Mouse CHSY1 Protein Mammalian Cell Mouse His
CHSY1-1679M Recombinant Mouse CHSY1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
CHSY1-1679M-B Recombinant Mouse CHSY1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Chsy1-784M Recombinant Mouse Chsy1 Protein, His&GST-tagged E.coli Mouse His&GST Leu601-Ala800

    Involved Pathway

    CHSY1 involved in several pathways and played different roles in them. We selected most pathways CHSY1 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHSY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways LDHBB,UGT1AB,ACADVL,KL,HAO1,GMPPAA,SRM,AANAT,CHPF2,CYCS
    Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate UST,CHST3B,B3GALT6,DSE,CHST14,CHSY3,CHPF,CHST3,CHST15,CHST12A

    Protein Function

    CHSY1 has several biochemical functions, for example, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity,glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHSY1 itself. We selected most functions CHSY1 had, and list some proteins which have the same functions with CHSY1. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding IHHB,CDK15,NR2F1A,CYP46A1.2,CNOT6,ACY3.1,U2AF1,RNF150A,SMYD5,ZNF143B
    glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity CSGALNACT1,CHPF,CHSY3
    N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity CHPF,CHPF2,CHSY3

    Interacting Protein

    CHSY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHSY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHSY1.

    dedA3;GOLT1B

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