CHST14
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Official Full Name
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 -
Overview
This gene encodes a member of the HNK-1 family of sulfotransferases. The encoded protein transfers sulfate to the C-4 hydroxyl of N-acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb-clubfoot syndrome. -
Synonyms
CHST14;carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14;D4ST1, dermatan 4 sulfotransferase 1;carbohydrate sulfotransferase 14;D4ST 1;HD4ST;D4st1;RP23-286G12.2;2600016L03Rik;ATCS;Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 14;CHSTE_HUMAN;D4ST-1;Dermatan 4-sulfotransferase 1;hD4ST1;UNQ1925/PRO4400;dermatan 4 sulfotransferase 1;HNK1ST
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- HEK293
- Mammalian Cell
- Wheat Germ
- In Vitro Cell Free System
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CHST14-100H | Recombinant Human CHST14, His-tagged | HEK293 | Human | His | 61-376 a.a. |
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| CHST14-12095Z | Recombinant Zebrafish CHST14 | Mammalian Cell | Zebrafish | His |
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| CHST14-1341H | Recombinant Human CHST14 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CHST14-3449M | Recombinant Mouse CHST14 Protein | Mammalian Cell | Mouse | His |
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| CHST14-1673M | Recombinant Mouse CHST14 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CHST14-1673M-B | Recombinant Mouse CHST14 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CHST14-1831HF | Recombinant Full Length Human CHST14 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 376 amino acids |
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Involved Pathway
CHST14 involved in several pathways and played different roles in them. We selected most pathways CHST14 participated on our site, such as Chondroitin sulfate/dermatan sulfate metabolism,Dermatan sulfate biosynthesis,Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Dermatan sulfate biosynthesis | BGNB,CSPG5B,DSEL,BGNA,UST,VCANB |
| Metabolism | BPNT1,COX7C,SLC5A2,AQP1A.1,CBLC-1,APOA4B.1,SLC25A1A,STAB2,ACOT6,MED7 |
| Chondroitin sulfate/dermatan sulfate metabolism | CSPG5B,GPC1A,VCANB,VCAN,B3GAT2,DCN,NCAN,CSPG4,BGN,Gpc2 |
| Metabolism of carbohydrates | STAB2,HS3ST6,HS3ST4,UST,SLC25A13,Gpc2,NHLRC1,SLC5A9,ST3GAL3A,B3GAT2 |
| Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | CSGALNACT1,CHST12,B4GALT7,B3GALT6,DSE,CSGALNACT2,CHST15,CHST3B,CHST3,CHPF2 |
| Glycosaminoglycan metabolism | SLC35B2,OGN,BGNA,SLC35D2,SLC26A1,PRELP,KIAA1199,CHP,HAS1,GPC1A |
Protein Function
CHST14 has several biochemical functions, for example, N-acetylgalactosamine 4-O-sulfotransferase activity,phosphate ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST14 itself. We selected most functions CHST14 had, and list some proteins which have the same functions with CHST14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphate ion binding | ADSS,SLC34A2,GNG12,OTC,MTHFD2,PNP,RPH3A,ADSSL1,SH2B3,RELA |
| N-acetylgalactosamine 4-O-sulfotransferase activity | SULT3ST4,HS3ST3L,HS6ST3B,HS3ST3B1B,SULT5A1,SULT2ST2,CHST9,SULT1ST8,SULT1ST7,SULT2ST3 |
Interacting Protein
CHST14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST14.
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