CENPN
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Official Full Name
centromere protein N -
Overview
The protein encoded by this gene forms part of the nucleosome-associated complex and is important for kinetochore;assembly. It is bound to kinetochores during S phase and G2 and recruits other proteins to the centromere. Pseudogenes;of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode;different protein isoforms. -
Synonyms
CENPN;centromere protein N;C16orf60, chromosome 16 open reading frame 60;BM039;FLJ13607;FLJ22660;BM 039;BM 309;BM-309;C16orf60;CENP N;CENP-N;CENPN_HUMAN;ICEN 32;ICEN32;Interphase centromere complex protein 32;OTTHUMP00000174973;OTTHUMP00000174974;OTTHUMP00000174975
Recombinant Proteins
- Rat
- Human
- Mouse
- Chicken
- Zebrafish
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CENPN-1335R | Recombinant Rat CENPN Protein | Mammalian Cells | Rat | His |
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| CENPN-254H | Recombinant Human CENPN Protein, GST-tagged | Wheat Germ | Human | GST |
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| CENPN-3291M | Recombinant Mouse CENPN Protein | Mammalian Cells | Mouse | His |
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| CENPN-3462C | Recombinant Chicken CENPN | Mammalian Cells | Chicken | His |
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| CENPN-490Z | Recombinant Zebrafish CENPN | Mammalian Cells | Zebrafish | His |
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| CENPN-7579HCL | Recombinant Human CENPN 293 Cell Lysate | HEK293 | Human | Non |
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| CENPN-1582M | Recombinant Mouse CENPN Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CENPN-1582M-B | Recombinant Mouse CENPN Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CENPN-1720HF | Recombinant Full Length Human CENPN Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 204 amino acids |
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| CENPN-993R | Recombinant Rat CENPN Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| CENPN-993R-B | Recombinant Rat CENPN Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
CENPN involved in several pathways and played different roles in them. We selected most pathways CENPN participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitotic Prometaphase | AHCTF1,MIS12,PANE1,SMC4,CENPO,KNTC1,PDS5A,NDC80,SGOL1,CENPC1 |
| M Phase | ENSAA,NCAPH2,STAG1,TMPO,MCPH1,ERCC6L,CENPC1,NUF2,DSN1,SET |
| Cell Cycle, Mitotic | NIPBL,ENSAA,CEP290,NCAPG2,LIN54,SMC4,CENPQ,CSNK2A2,TUBB4A,DCTN3 |
| Mitotic Metaphase and Anaphase | SPC24,SGOL1,PMF1,CENPH,WAPAL,SKA1,MIS12,SPC25,CENPE,VRK1 |
| Deposition of new CENPA-containing nucleosomes at the centromere | CENPK,CENPL,MIS18BP1,RBBP4,NPM1,OIP5,CENPP,CENPO,CENPC1,MIS18A |
| Cell cycle | NIPBL,PMF1,CCNA1,HTATIP,BARD1,TUBGCP3,CDC23,CSNK1E,CEP76,H3F3D |
| Chromosome Maintenance | OIP5,MIS18BP1,NPM1,TINF2,SMARCA5,POLD3,CENPW,CENPQ,CENPI,CENPP |
| Mitotic Anaphase | CENPL,B9D2,VRK2,RANGAP1B,ZWINT,NDEL1A,MIS12,ZW10,SGOL1,NDEL1B |
Protein Function
CENPN has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CENPN itself. We selected most functions CENPN had, and list some proteins which have the same functions with CENPN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CENPN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPN here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPN.
AKTIP;ITGB3BP;CENPU;CENPQ;CENPO;Cenph
Resources
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References
- Dunemann, F; Schrader, O; et al. Characterization of Centromeric Histone H3 (CENH3) Variants in Cultivated and Wild Carrots (Daucus sp.). PLOS ONE 9:-(2014).
- Mahler, M; Satoh, M; et al. Autoantibodies to the Rpp25 Component of the Th/To Complex are the Most Common Antibodies in Patients with Systemic Sclerosis without Antibodies Detectable by Widely Available Commercial Tests. JOURNAL OF RHEUMATOLOGY 41:1334-1343(2014).
