CENPH

  • Official Full Name

    centromere protein H

  • Overview

    Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.

  • Synonyms

    CENPH;centromere protein H;NNF1;MIND kinetochore complex component;homolog (S. cerevisiae);PMF1;CENP H;CENP-H;CENPH_HUMAN;ICEN35;Interphase centromere complex protein 35;Kinetochore protein CENP H;NNF1, MIND kinetochore complex component, homolog;OTTHUMP00000123477;OTTHUMP00000221978;OTTHUMP00000221979;kinetochore protein CENP-H

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Zebrafish
  • E.coli
  • Wheat Germ
  • Mammalian Cells
  • Human
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CENPH-11095H Recombinant Human CENPH, His-tagged E.coli Human His 1-247a.a.
CENPH-1116H Recombinant Human CENPH Protein, GST-Tagged Wheat Germ Human GST
CENPH-26924TH Recombinant Human CENPH, His-tagged E.coli Human His 112 amino acids
CENPH-27395TH Recombinant Human CENPH, His-tagged E.coli Human His 9-247 a.a.
CENPH-325H Recombinant Human CENPH Protein, His-tagged E.coli Human His Met1~Met247
Cenph-326M Recombinant Mouse Cenph Protein, His-tagged E.coli Mouse His Glu28~Leu241
CENPH-3285M Recombinant Mouse CENPH Protein Mammalian Cells Mouse His
CENPH-3644H Recombinant Human CENPH, His-tagged Human Human His
CENPH-6179C Recombinant Chicken CENPH Mammalian Cells Chicken His
CENPH-6340Z Recombinant Zebrafish CENPH Mammalian Cells Zebrafish His
CENPH-7584HCL Recombinant Human CENPH 293 Cell Lysate HEK293 Human Non
CENPH-1578M Recombinant Mouse CENPH Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
CENPH-1578M-B Recombinant Mouse CENPH Protein Pre-coupled Magnetic Beads HEK293 Mouse
Cenph-2104M Recombinant Mouse Cenph Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
CENPH-2687H Recombinant Human CENPH protein, GST-tagged E.coli Human GST 1-247aa
CENPH-3320HF Recombinant Full Length Human CENPH Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 247 amino acids
CENPH-745H Recombinant Human CENPH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc

    Involved Pathway

    CENPH involved in several pathways and played different roles in them. We selected most pathways CENPH participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mitotic Anaphase NDC80,DSN1,CDCA8,VRK2,B9D2,SPDL1,CENPN,NSL1,CLIP1,PDS5A
    M Phase PMF1,CLIP1,ANKLE2,KIF2A,SGOL1,GORASP2,CNEP1R1,CDCA5,CENPK,INCENP
    Deposition of new CENPA-containing nucleosomes at the centromere CENPC1,CENPW,CENPP,NPM1,RBBP7,CENPK,CENPL,MIS18BP1,CENPQ,RBBP4
    Mitotic Prometaphase CDCA5,NDC80,CENPL,SMC2,PDS5A,CCDC99,SPDL1,SMC4,DSN1,RANGAP1B
    Mitotic Metaphase and Anaphase PMF1,WAPAL,SPC25,INCENP,CCDC99,CENPP,KNTC1,ERCC6L,CDCA5,RANGAP1B
    Cell Cycle, Mitotic HIST4H4,SGOL2,RANGAP1B,GORASP1,NDE1,GOLGA2,SPC25,ODF2,MCM10,GMNN
    Cell cycle SPC25,NEK6,PRKDC,MCM6,BABAM1,LIN9,GADD45AA,MAD2L2,CLSPN,DCTN2
    Chromosome Maintenance MIS18A,DNA2,PANE1,WRAP53,MIS18BP1,POT1,MLF1IP,ITGB3BP,NPM1,RBBP4

    Protein Function

    CENPH has several biochemical functions, for example, kinetochore binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPH itself. We selected most functions CENPH had, and list some proteins which have the same functions with CENPH. You can find most of the proteins on our site.

    Function Related Protein
    kinetochore binding CLASP1A,CLASP1,SPDL1,CCDC99
    protein binding CCT2,VDR,MLF1,CADM1,SPAG9,TTC5,BTN3A1,TMEM88,PITPNM3,ZNF193

    Interacting Protein

    CENPH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPH here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPH.

    MTAP;CENPK;PMVK;EMC1;NDC80;q8xb62_eco57;CENPU;CENPQ;Cenpi;CENPO

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