CDK5R1
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Official Full Name
cyclin-dependent kinase 5, regulatory subunit 1 (p35) -
Synonyms
CDK5R1;cyclin-dependent kinase 5, regulatory subunit 1 (p35);cyclin-dependent kinase 5 activator 1;Nck5a;p35nck5a;CDK5 activator 1;neuronal CDK5 activator;TPKII regulatory subunit;regulatory partner for CDK5 kinase;tau protein kinase II 23kDa subunit;cyclin-dependent kinase 5 regulatory subunit 1;p23;p25;p35;CDK5R;NCK5A;CDK5P35;MGC33831
Recombinant Proteins
- Human
- Rat
- Mouse
- Bovine
- Rhesus macaque
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
CDK5R1 involved in several pathways and played different roles in them. We selected most pathways CDK5R1 participated on our site, such as Alzheimers disease,Cocaine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK5R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cocaine addiction | MAOA,GRIN2D,PDYN,PRKACA,SLC18A2,GNAI1,RGS9,GRIN1,CDK5,GRM3 |
| Alzheimers disease | ATP5A1,CAPN2,NDUFS1,CASP12,APBB1,COX7B,CYCS,NDUFS3,NDUFB3,NDUFS8 |
Protein Function
CDK5R1 has several biochemical functions, for example, cadherin binding,calcium ion binding,cyclin-dependent protein kinase 5 activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK5R1 itself. We selected most functions CDK5R1 had, and list some proteins which have the same functions with CDK5R1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cadherin binding | FXYD5,CTNNA2,NDRG1,NUMB,VCL,MMP24,CTNNB1,PROM1,AKAP5,JUPA |
| kinase activity | ITPK1A,IGF1RA,LMTK2,CAMK1DA,PRKAR2AA,NME2B.2,FAM20B,STK24B,STK35L,PKMYT1 |
| cyclin-dependent protein serine/threonine kinase activity | CDK1,CDK16,CDKL1,CDK11B,CDK3,CDK12,CDK13,CCND3,STK30,CDK8 |
| ephrin receptor binding | EFNB1,EFNB2,PTPN1,CRK,EFNB3,EFNB3B,SRC,FYN,PIK3CG,EPHA4 |
| protein kinase activity | SGK196,NEK4,STK25B,GUCY2F,MINK1,DYRK3,cka1,PHKG1B,PINK1,PRKAG1 |
| protein kinase binding | FER,MAPT,STAT3,GRB7,LAT,HSPB1,CCNE1,KCNA5,TPRKB,MVP |
| calcium ion binding | SPTA1,DSG1,NINL,SULF2B,ANXA9,PLA2G2F,RASGRP2,ITSN1,FBN1,MBL1 |
| protein serine/threonine kinase activator activity | ALS2,CALM3,MAP2K2,STK4,SPRY2,MAP2K1,STK3,FAM20A,IGF2,CALM2 |
| protein binding | PTI,PPP1R37,HSPA2,TERF1,CCDC59,BARD1,RPN1,TUBA3E,ZNF26,KRTAP3-3 |
Interacting Protein
CDK5R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK5R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK5R1.
CDK5;AATK;MTUS2;AATK;q53fc7_human;AATK;q96be0_human
Resources
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References
- Zuccotti, P; Colombrita, C; et al. hnRNPA2/B1 and nELAV proteins bind to a specific U-rich element in CDK5R1 3 '-UTR and oppositely regulate its expression. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 1839:506-516(2014).
- Daval, M; Gurlo, T; et al. Cyclin-Dependent Kinase 5 Promotes Pancreatic beta-Cell Survival via Fak-Akt Signaling Pathways. DIABETES 60:1186-1197(2011).
