CDH15
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Official Full Name
Cadherin 15, Type 1, M-cadherin (Myotubule) -
Overview
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. -
Synonyms
cadherin 15, type 1, M-cadherin (myotubule);CDH3;cadherin-15;cadherin-3;cadherin-14;CDHM;MCAD;MRD3;CDH14;CDH15;muscle-cadherin;OTTHUMP00000175347;M-cadherin;Muscle cadherin
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Rat
- Mus musculus
- Mammalian Cell
- E.coli
- Human Cell
- HEK293
- E.coli expression system
- His
- His&T7
- Fc
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDH15-11885Z | Recombinant Zebrafish CDH15 | Mammalian Cell | Zebrafish | His |
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| Cdh15-2093M | Recombinant Mouse Cdh15 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Leu60~Phe374 |
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| CDH15-3167M | Recombinant Mouse CDH15 Protein | Mammalian Cell | Mouse | His |
|
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| CDH15-50H | Recombinant Human CDH15 protein, T7/His-tagged | E.coli | Human | His&T7 | 61-246 a.a. |
|
| Cdh15-7476R | Recombinant Rat Cdh15, Fc tagged | Human Cell | Rat | Fc | 1-602 a.a. |
|
| CDH15-1484RCL | Recombinant Rat CDH15 cell lysate | Human Cell | Rat | Non |
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| CDH15-0805H | Recombinant Human CDH15 Protein (Leu61-Phe260), N-His tagged | E.coli | Human | His | Leu61-Phe260 |
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| CDH15-1506M | Recombinant Mouse CDH15 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CDH15-1506M-B | Recombinant Mouse CDH15 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RFL28981MF | Recombinant Full Length Mouse Cadherin-15(Cdh15) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (60-784) |
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| RFL31388HF | Recombinant Full Length Human Cadherin-15(Cdh15) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (61-814) |
|
Involved Pathway
CDH15 involved in several pathways and played different roles in them. We selected most pathways CDH15 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | JAM2A,CNTN1,PVR,PVRL3,NRCAMA,CLDNG,ICOS,HLA-DPA1,CD99,CD274 |
Protein Function
CDH15 has several biochemical functions, for example, calcium ion binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH15 itself. We selected most functions CDH15 had, and list some proteins which have the same functions with CDH15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | NOTCH1A,ZIC4,PPM1E,DGKAA,ZHX3,YME1L1,PHF23A,TRAF4B,NINL,NRXN2 |
| protein binding | ERLIN2,FCN3,CCDC137,TESK2,PDCD6,CD300LD,TMEM115,PXN,NR2E3,POR |
| calcium ion binding | LOC100686744,PVALB2,CALML4A,PDCD6,AKR1C1,SYT1A,MBL1,PCDH1G1,PEF1,PCDH1GC6 |
Interacting Protein
CDH15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH15 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH15.
Resources
Research Area
Muscle Stem Cell MarkersMyogenesis Markers
Cadherin Superfamily
Myogenic Precursor Markers
Cadherins
Related Services
Related Products
References
- Storer, NY; White, RM; et al. Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis. DEVELOPMENT 140:3040-3050(2013).
- Bartnik, M; Szczepanik, E; et al. Application of array comparative genomic hybridization in 102 patients with epilepsy and additional neurodevelopmental disorders. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 159B:760-771(2012).
