CD96
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Official Full Name
CD96 molecule -
Overview
CD96, known as Tactile (T cell-activated increased late expression), is a 160 kD type I transmembrane glycoprotein and is a member of the Ig superfamily molecules. It is expression on NK cells, T cells (up-regulated upon activation), and some acute myeloi -
Synonyms
CD96;CD96 molecule;CD96 antigen;T-cell surface protein tactile;TACTILE;cell surface antigen CD96;T cell activation, increased late expression;t cell-activated increased late expression protein;MGC22596;DKFZp667E2122
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Rat
- HEK293
- E.coli
- Mammalian cells
- C-His
- Wheat Germ
- Mammalian Cell
- Human Cell
- Human Cells
- HEK293T
- In Vitro Cell Free System
- E.coli expression system
- His
- His&T7
- His&Avi
- Non
- GST
- His&mFc
- Flag
- His&Fc&Avi
- Myc&DDK
- Fc&Avi
- mFc
- Fc
Involved Pathway
CD96 involved in several pathways and played different roles in them. We selected most pathways CD96 participated on our site, such as Adaptive Immune System,Immune System,Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD96 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | Siglece,CD200R1,ASB3,KLB,ITPR2,ASB6,CTLA4,FRS2,UBA5,UBE2V2 |
| Immune System | IFI27,PCBP2,CLEC5A,DCTN3,PVRL2L,MGC174857,AP1S1,CRTAM,AP1B1,KLHL21 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | LILRB2,SIGLEC9,SIGLEC5,CD300LG,SIGLEC10,CD200,CD300LB,CD200R3,CD300LD,OSCAR |
Protein Function
CD96 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CD96 itself. We selected most functions CD96 had, and list some proteins which have the same functions with CD96. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CD96 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD96 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD96.
hemH1
Resources
Research Area
Cancer Drug TargetsNectin and Nectin-like Ligand/Receptor Co-Signaling Molecules
Co-stimulatory Molecules
Leukemia Cancer Stem Cell Markers
Immune Checkpoints
Related Services
Related Products
References
- Staudinger, M; Kellner, C; et al. Depletion of leukemic AML stem cells from autografts by CD96 antibody TH111. ONCOLOGY RESEARCH AND TREATMENT 37:128-128(2014).
- Staudinger, M; Kellner, C; et al. Elimination of AML leukemic stem cells by CD96 antibody as a new strategy in stem cell transplantation. ONKOLOGIE 36:208-208(2013).
