CCL4L2
-
Official Full Name
chemokine (C-C motif) ligand 4-like 2 -
Overview
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. -
Synonyms
CCL4L2;chemokine (C-C motif) ligand 4-like 2;CC chemokine ligand 4L2;CC chemokine ligand 4L1d2;lymphocyte activation gene 1;macrophage inflammatory protein-1b2;chemokine (C-C motif) ligand 4-like 1, telomeric;CCL4L;SCYA4L;AT744.2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CCL4L2-627H |
Active Recombinant Human CCL4L2
|
E.coli | Human | Non | 24-92 a.a. |
|
| CCL4L2-27831TH | Recombinant Human CCL4L2, His-tagged | E.coli | Human | His | 69 amino acids |
|
| CCL4L2-1189H | Recombinant Human CCL4L2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
Involved Pathway
CCL4L2 involved in several pathways and played different roles in them. We selected most pathways CCL4L2 participated on our site, such as Cytokine-cytokine receptor interaction,Chemokine signaling pathway,NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL4L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Toll-like receptor signaling pathway | PIK3R1,MAPK8,TLR2-2,PIK3R5,IFNA7,IKBKE,AKT2,MAPK3,IRAK1,IL12A |
| NF-kappa B signaling pathway | LAT,BIRC3,TNFRSF1A,NFKBIA,IRAK1,BCL2L1,DDX58,VCAM1,CD40,LRDD |
| Salmonella infection | RAB7,ACTB2,PKN2,CXCL8B.3,ROCK1,MAPK8,NOS2A,IFNG,ACTG1,CDC42L |
| Cytosolic DNA-sensing pathway | RIPK1,POLR3C,POLR2F,RIPK3,POLR2E,DDX58,POLR2L,IFNPHI3,CCL5,NFKBIA |
| Cytokine-cytokine receptor interaction | TNFSF8,IL11,CNTFR,TNFSF13B,CCL4,CXCR3,CX3CL1,CCL26,FIGF,TNFRSF10C |
| Chemokine signaling pathway | Adcy4,RLN1,CCL19,GNB2,Ccl21c,RAP1A,AKT2,PTK2B,CCR10,CXCL2 |
Protein Function
CCL4L2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CCL4L2 itself. We selected most functions CCL4L2 had, and list some proteins which have the same functions with CCL4L2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CCL4L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL4L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL4L2.
SLC30A2
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