CASQ2

  • Official Full Name

    calsequestrin 2 (cardiac muscle)

  • Overview

    The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin;is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding;protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular;tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease;characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

  • Synonyms

    CASQ2;calsequestrin 2 (cardiac muscle);calsequestrin-2;PDIB2;calsequestrin, cardiac muscle isoform;calsequestrin 2, fast-twitch, cardiac muscle;FLJ26321;FLJ93514

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Zebrafish
  • Canine
  • Wheat Germ
  • Mammalian Cells
  • Human
  • HEK293
  • E.coli
  • In Vitro Cell Free System
  • Dog Heart
  • GST
  • His
  • Non
  • Avi
  • Fc
  • T7
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CASQ2-0436H Recombinant Human CASQ2 Protein, GST-Tagged Wheat Germ Human GST
CASQ2-2760M Recombinant Mouse CASQ2 Protein Mammalian Cells Mouse His
CASQ2-4248H Recombinant Human Calsequestrin 2 (Cardiac Muscle), His-tagged Human Human His 20-399 a.a.
CASQ2-6095C Recombinant Chicken CASQ2 Mammalian Cells Chicken His
CASQ2-789Z Recombinant Zebrafish CASQ2 Mammalian Cells Zebrafish His
CASQ2-7826HCL Recombinant Human CASQ2 293 Cell Lysate HEK293 Human Non
CASQ2-032H Recombinant Human calsequestrin 2 Protein, His tagged HEK293 Human His 20-399aa
CASQ2-1250M Recombinant Mouse CASQ2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
CASQ2-1250M-B Recombinant Mouse CASQ2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Casq2-1745M Recombinant Mouse Casq2 protein, His & T7-tagged E.coli Mouse His&T7 Glu20~Lys320 (Accession # O09161)
CASQ2-2750HF Recombinant Full Length Human CASQ2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 399 amino acids
CASQ2-301241H Recombinant Human CASQ2 protein, GST-tagged E.coli Human GST Phe273-Glu399
CASQ2-30C Native Canine CASQ2 Dog Heart Canine Non
CASQ2-6334H Recombinant Human CASQ2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Casq2-775M Recombinant Mouse Casq2 Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    CASQ2 involved in several pathways and played different roles in them. We selected most pathways CASQ2 participated on our site, such as Calcium Regulation in the Cardiac Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CASQ2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium Regulation in the Cardiac Cell CX30.3,CX35.4,KCNB1,CHRM5,RGS16,GJC1,CX27.5,RGS5A,FKBP1A,PKIB

    Protein Function

    CASQ2 has several biochemical functions, for example, calcium ion binding,calcium-dependent protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CASQ2 itself. We selected most functions CASQ2 had, and list some proteins which have the same functions with CASQ2. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding MMP15,CAPN2B,SPNA2,SRI,SLC24A4A,SPARCL1,GCH1,CDH5,PCDHGA4,CAPN11
    protein binding ATXN1,KCNE3,PPP1CC,CRNKL1,CYFIP2,CLIP4,GAB1,GAP43,VAPB,CCDC28B
    protein homodimerization activity SOD1,NCR3,ABCB10,CTBP2A,ASGR1,PITX2,VAPB,BMP4,NTRK2,DAXX
    calcium-dependent protein binding S100A6,S100P,KOP,ANXA2,RAC3,KCNIP3,SLC9A1,MASP2,CHP,ANXA4
    protein kinase C binding PRKCB,PKN1,UGT1A7,HDAC7,FEZ1,AVPR1B,DACT1,TOP2B,SDPRB,FLNA

    Interacting Protein

    CASQ2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CASQ2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CASQ2.

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