CALU
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Official Full Name
calumenin -
Overview
The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
CALU;calumenin;CALU_HUMAN;Crocalbin;crocalbin-like protein;FLJ90608;IEF SSP 9302;multiple EF-hand protein;OTTHUMP00000212712;OTTHUMP00000212713;OTTHUMP00000212714;OTTHUMP00000212715
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Wheat Germ
- E.coli
- Mammalian Cells
- HEK293
- Human Cells
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
CALU involved in several pathways and played different roles in them. We selected most pathways CALU participated on our site, such as Hemostasis,Platelet activation, signaling and aggregation,Platelet degranulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CALU were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Platelet activation, signaling and aggregation | F13A1A.1,PDPN,BRPF3,MMRN1,WDR1,IGF2B,ABHD12,CLU,RHOGA,SCG3 |
| Hemostasis | DOCK6,KIF5A,KLC3,NADL1.1,CAP1,KIF2A,MMRN1,ITGB3A,RAPGEF3,SLC7A8A |
| Response to elevated platelet cytosolic Ca2+ | SPARC,WDR1,TFA,IGF2B,MMRN1,STXBP3A,PLEK,F13A1B,SRGN,MMRN2A |
| Platelet degranulation | WDR1,GAS6,SERPINF2B,CD9B,F13A1B,MMRN1,SRGN,BRPF3,CD9A,F13A1A.1 |
Protein Function
CALU has several biochemical functions, for example, calcium ion binding,enzyme binding,enzyme inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CALU itself. We selected most functions CALU had, and list some proteins which have the same functions with CALU. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enzyme binding | RPS2,GSTM3,PRTN3,MLL5,APP,NPM2,GSTM4,TSPAN10,ATG3,UGT1A3 |
| calcium ion binding | MMP14,RHOT1A,ITPR3,RCN2,JAG1,DGKA,RCN3,BGLAP-RS1,CAPN3,SLIT1 |
| protein binding | BAG5,SOCS3,TIMM44,ARHGEF16,CCR5,C22orf28,HBXIP,MNAT1,ARHGEF12,PYYA |
| enzyme inhibitor activity | NOTCH1,KIAA1967,UGT1A1,APBA3,PDE6G,PLN,CSN2,FRY,TXNIP,DGKZ |
Interacting Protein
CALU has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CALU here. Most of them are supplied by our site. Hope this information will be useful for your research of CALU.
UBQLN1;RAF1;AURKA;Trim28;Mis12;Mad2l2;PRMT5;UMPS;ZPBP;CTNNAL1;Cenpe;IRS4;MAST3;env;ARAF;HSPA5;CFTR
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References
- Choi, SI; Kim, SY; et al. TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1. ONCOTARGET 5:9823-9837(2014).
- Qin, T; Yin, YY; et al. Whole inactivated avian Influenza H9N2 viruses induce nasal submucosal dendritic cells to sample luminal viruses via transepithelial dendrites and trigger subsequent DC maturation. VACCINE 33:1382-1392(2015).
