CABIN1
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Official Full Name
calcineurin binding protein 1 -
Overview
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011] -
Synonyms
CABIN1;calcineurin binding protein 1;CAIN;PPP3IN;calcineurin-binding protein cabin-1;calcineurin inhibitor;calcineurin binding protein cabin 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CABIN1-0255H | Recombinant Human CABIN1 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CABIN1-8082Z | Recombinant Zebrafish CABIN1 | Mammalian Cells | Zebrafish | His |
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| CABIN1-577H | Recombinant Human CABIN1 Protein, His/GST-tagged | E.coli | Human | His&GST | Ser23~Glu288 |
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| Cabin1-578M | Recombinant Mouse Cabin1 Protein, His-tagged | E.coli | Mouse | His | Ser11~Pro289 |
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Involved Pathway
CABIN1 involved in several pathways and played different roles in them. We selected most pathways CABIN1 participated on our site, such as Cellular Senescence,Cellular responses to stress,DNA Damage/Telomere Stress Induced Senescence, which may be useful for your reference. Also, other proteins which involved in the same pathway with CABIN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| T cell receptor signaling pathway | PIK3R2,PAK7,CD3E,PRKCQ,PIK3CA,NFKBIE,LCK,RELA,GRB2,VAV2 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | HIST1H1C,HIST1H1E,HIST1H1A,HIST1H1B,UBN1,HIRA,H1F0,HMGA1B,HIST1H1D,HMGA1-RS1 |
| DNA Damage/Telomere Stress Induced Senescence | TERF1,HIRA,HMGA1-RS1,HIST1H1B,H1F0,HMGA1B,TERF2,HTATIP,ASF1A,ACD |
| Cellular responses to stress | DNAJC7,HSBP1A,HIST2H3C,ST13,TXN,ERF,KDM6B,LAMTOR1,DPF1,HIF3A |
| Cellular Senescence | EED,IGFBP7,SUZ12B,RBBP7,HIST1H1E,SUZ12,HMGA1-RS1,CBX8A,MOV10,HTATIP |
Protein Function
CABIN1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CABIN1 itself. We selected most functions CABIN1 had, and list some proteins which have the same functions with CABIN1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
CABIN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CABIN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CABIN1.
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