C1QTNF6
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Official Full Name
C1q and tumor necrosis factor related protein 6 -
Overview
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration. -
Synonyms
ZACRP6;C1q and tumor necrosis factor related protein 6;C1QT6_HUMAN;C1QTNF6;Complement C1q tumor necrosis factor related protein 6;Complement C1q tumor necrosis factor-related protein 6;CTRP 6;CTRP6;OTTHUMP00000197772;OTTHUMP00000197774;PRO1151;UNQ581;complement-c1q tumor necrosis factor-related protein 6
Recombinant Proteins
- Rat
- Human
- Mouse
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- Yeast
- Mammalian cells
- His
- Flag
- Non
- Myc&DDK
- N-His-sumostar
- His&Fc&Avi
- N-His-SUMO
Involved Pathway
C1QTNF6 involved in several pathways and played different roles in them. We selected most pathways C1QTNF6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with C1QTNF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
C1QTNF6 has several biochemical functions, for example, identical protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C1QTNF6 itself. We selected most functions C1QTNF6 had, and list some proteins which have the same functions with C1QTNF6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | KCNJ2,SOD2,SMAD3,CCL4,TTR,L3MBTL1,KCNIP2,KHDC1A,GLUD1,SERPINA1 |
| protein binding | NR5A1,OCA2,ABI3,MPZL3,PLOD3,DISC1,STIM1,ISOC1,CDC40,TPRKB |
Interacting Protein
C1QTNF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1QTNF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of C1QTNF6.
SGTA;Ring1;PML;ANAPC15;Ppp6r1;Mad2l1bp;Ndel1;VPS16;Cenph
Resources
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References
- Zhao, SX; Xue, LQ; et al. Robust evidence for five new Graves disease risk loci from a staged genome-wide association analysis. HUMAN MOLECULAR GENETICS 22:3347-3362(2013).
- Johnen, G; Rozynek, P; et al. Cross-Contamination of a UROtsa Stock with T24 Cells - Molecular Comparison of Different Cell Lines and Stocks. PLOS ONE 8:-(2013).
