BMP2K
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Official Full Name
BMP2 inducible kinase -
Overview
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
BMP2K;BMP2 inducible kinase;BMP-2-inducible protein kinase;BIKe;DKFZp434K0614;HRIHFB2017;DKFZp434P0116
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Mammalian Cell
- Sf9 Insect Cell
- Wheat Germ
- HEK293
- HEK293T
- E.coli
- Mammalian cells
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
- N-His&C-Myc
- Flag
Involved Pathway
BMP2K involved in several pathways and played different roles in them. We selected most pathways BMP2K participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP2K were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transcriptional misregulation in cancer | BCL2A1,IL2RB,PDGFA,WHSC1,MLF1,Aff1,SS18,RARA,MET,TGFBR2 |
Protein Function
BMP2K has several biochemical functions, for example, ATP binding,phosphatase regulator activity,protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP2K itself. We selected most functions BMP2K had, and list some proteins which have the same functions with BMP2K. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatase regulator activity | PPP1R12B,PPP1R12A,MTMR12,SBF1 |
| ATP binding | PTK2B,UBA7,SMOK2B,DDX20,ZNF143B,NMRK2,FGFR1B,UBE2K,NSFA,PSKH2 |
| protein serine/threonine kinase activity | DAPK1,RIPK4,Aatk,STK32C,PASK,SIK3,NLK2,MAP3K2,SLK,HUNK |
Interacting Protein
BMP2K has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP2K here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP2K.
BCR/ABL fusion;czc8004;linkable sunitinib analogue;bosutinib;imatinib;dasatinib;midostaurin;crizotinib;Sec24c;Flot1;GAK;SEC16A;FN1;GBA;CLTB;FLNA;CDK2;MYH9
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