BCAS1
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Official Full Name
breast carcinoma amplified sequence 1 -
Overview
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. -
Synonyms
BCAS1;breast carcinoma amplified sequence 1;breast carcinoma-amplified sequence 1;AIBC1;NABC1;novel amplified in breast cancer 1;amplified and overexpressed in breast cancer
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- Yeast
- In Vitro Cell Free System
- HEK293T
- HEK293
- E.coli
- GST
- His
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BCAS1-123H | Recombinant Human BCAS1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| BCAS1-124H | Recombinant Human BCAS1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| BCAS1-1340H | Recombinant Human BCAS1 Protein (1-584 aa), His-tagged | Yeast | Human | His | 1-584 aa |
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| BCAS1-1601HF | Recombinant Full Length Human BCAS1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 584 amino acids |
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| Bcas1-1842M | Recombinant Mouse Bcas1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| BCAS1-2368H | Recombinant Human BCAS1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| BCAS1-352H | Recombinant Human BCAS1 Protein (1-584 aa), GST-tagged | E.coli | Human | GST | 1-584 aa |
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Involved Pathway
BCAS1 involved in several pathways and played different roles in them. We selected most pathways BCAS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BCAS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
BCAS1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by BCAS1 itself. We selected most functions BCAS1 had, and list some proteins which have the same functions with BCAS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
BCAS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCAS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCAS1.
Resources
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References
- Crisp, JL; Savariar, EN; et al. Dual Targeting of Integrin alpha(v)beta(3) and Matrix Metalloproteinase-2 for Optical Imaging of Tumors and Chemotherapeutic Delivery. MOLECULAR CANCER THERAPEUTICS 13:1514-1525(2014).
- Yip, WK; Choo, CW; et al. Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala Lumpur, Malaysia. APMIS 121:954-966(2013).
