BAZ2A
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Official Full Name
bromodomain adjacent to zinc finger domain, 2A -
Overview
BAZ2A is a bromodomain adjacent to a zinc finger domain protein. It may play a role in transcriptional regulation interacting with ISWI and may serve a specific role in maintaining or altering the chromatin structure of the rDNA locus. BAz2A colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. -
Synonyms
BAZ2A;bromodomain adjacent to zinc finger domain, 2A;TIP5;WALp3;bromodomain adjacent to zinc finger domain protein 2A;hWALp3;TTF-I interacting peptide 5;TTF-I-interacting protein 5;transcription termination factor I-interacting protein 5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BAZ2A-098H | Recombinant Human BAZ2A Protein, GST-tagged | Wheat Germ | Human | GST |
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| BAZ2A-1605Z | Recombinant Zebrafish BAZ2A | Mammalian Cells | Zebrafish | His |
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| BAZ2A-59H | Recombinant Human BAZ2A protein, GST-tagged | E.coli | Human | GST | 1787-1901 |
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| BAZ2A-60H | Recombinant Human BAZ2A protein, His-tagged | E.coli | Human | His | 1787-1901 |
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| RFL22886OF | Recombinant Full Length Oryza Sativa Subsp. Japonica Probable Aquaporin Tip5-1(Tip5;1) Protein, His-Tagged | E.coli | Rice | His | Full L. Full Length (1-269) |
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Involved Pathway
BAZ2A involved in several pathways and played different roles in them. We selected most pathways BAZ2A participated on our site, such as Epigenetic regulation of gene expression,Gene Expression,Negative epigenetic regulation of rRNA expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with BAZ2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Epigenetic regulation of gene expression | SAP30L,MTF2,DNMT3B,SUZ12,H3F3D,DNMT1,JARID2,TET3,SAP30BP,JARID2B |
| Gene Expression | ZNF79,ZNF786,ZNF484,PTRF,MAPKAPK2B,ADAR,ZNF454,ZNF486,BRF1B,MED25 |
| Negative epigenetic regulation of rRNA expression | SAP30L,SUDS3,SIN3B,TAF1D,SAP18,CD3EAP,EFCAB11,SAP130,RRP8,SAP30BP |
| NoRC negatively regulates rRNA expression | SIN3B,DNMT3B,CD3EAP,TAF1A,DNMT1,SAP130,SAP30L,SUDS3,TAF1C,SAP30BP |
Protein Function
BAZ2A has several biochemical functions, for example, RNA binding,RNA polymerase I CORE element sequence-specific DNA binding,histone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BAZ2A itself. We selected most functions BAZ2A had, and list some proteins which have the same functions with BAZ2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GRID2IP,PYGB,CEP104,SPG7,AKT2,PKD1L3,ZNF524,ADH1A,POC1A,CFH |
| RNA polymerase I CORE element sequence-specific DNA binding | SMARCB1,TAF1C,SMARCA4,PIH1D1,EFCAB11,RRN3,TAF1B |
| RNA binding | DIS3,ADAT1,SCAF1,SRRM4,OASL1,MARF1,RNMT,RBMS3,HNRNPH2,IGF2BP3 |
| ligand-dependent nuclear receptor binding | MED1,NCOR1,TRIM24,NCOR2,ISL1,SRA1,NCOA2,SMARCD3,TADA3,SMARCE1 |
| lysine-acetylated histone binding | TAF1L,PHIP,CARM1,MLL1,PSME4B,BRD2,BRD3,TRIM24,BRD7,BRD4 |
| histone binding | NPM1,CHD2,PRKCBB,SNCA,ASF1A,UHRF1,HIST1H4C,HIST2H4A,PRKCBP1L,NPM2 |
| zinc ion binding | ARIH1,USP44,NR5A1A,RBM5,TEX13A,MKRN3,QTRTD1,LONRF2,TRIM35-27,PHF1 |
Interacting Protein
BAZ2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BAZ2A here. Most of them are supplied by our site. Hope this information will be useful for your research of BAZ2A.
ABL1;FYN;NCK1;GRB2;BAZ1B;PYHIN1;TRIM33;FBL
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