B9D2
-
Official Full Name
B9 protein domain 2 -
Overview
This gene encodes a B9 domain protein, which are exclusively found in ciliated organisms. The gene is upregulated during mucociliary differentiation, and the encoded protein localizes to basal bodies and cilia. Disrupting expression of this gene results in ciliogenesis defects. -
Synonyms
B9D2;B9 protein domain 2;B9 domain-containing protein 2;MGC4093;MKS1-related protein 2;involved in cIlia stability-1;MKS10;MKSR2;ICIS-1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
B9D2 involved in several pathways and played different roles in them. We selected most pathways B9D2 participated on our site, such as Anchoring of the basal body to the plasma membrane,Assembly of the primary cilium,Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with B9D2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitotic Metaphase and Anaphase | PDS5B,CENPE,RANGAP1B,CDCA8,CDCA5,VRK2,CLIP1,PMF1,NUDC,TMPO |
| Cell cycle | ORC6L,YWHAH,CDC27,NDE1,GADD45BB,MCM3,TERF2IP,BANF1,CDK6,MPEG1 |
| Mitotic Prometaphase | AHCTF1,MIS12,NDEL1A,SKA1,CENPC1,SGOL2,CENPO,NUF2,SMC2,NSL1 |
| Cell Cycle, Mitotic | CDCA8,KIF20A,NUPL2,SPDL1,MCM10,NIPBL,CTDNEP1B,ENSAB,KNTC1,DCTN1A |
| M Phase | KIF18A,ERCC6L,APITD1,NUDC,NSL1,LEMD3,CLIP1,NDEL1,ITGB3BP,SPC25 |
| Mitotic Anaphase | CENPP,RANGAP1B,CENPE,CENPH,INCENP,PMF1,SKA2,CENPO,MIS12,PANE1 |
| Assembly of the primary cilium | DYNLL2B,BBS9,BBS10,CCT2,EXOC6,CYS1,TRIP11,RP2,KIF3C,BBS1 |
| Anchoring of the basal body to the plasma membrane | CEP164,CEP76,CEP63,CSNK1D,CENPJ,NEK2,CEP135,CKAP5,CEP152,CEP72 |
Protein Function
B9D2 has several biochemical functions, for example, gamma-tubulin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by B9D2 itself. We selected most functions B9D2 had, and list some proteins which have the same functions with B9D2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CHRNA5,DACT1,LYL1,DSN1,PVRL2,CDA,FCER2,STX5,OSBPL3,AGER |
| gamma-tubulin binding | TUBGCP5,PDE4B,NDN,SPATC1,TUBGCP4,TUBGCP2,RAB11FIP5,FEZ1,RACGAP1,RAD51D |
Interacting Protein
B9D2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B9D2 here. Most of them are supplied by our site. Hope this information will be useful for your research of B9D2.
INVS;TTC30B
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