AZU1

  • Official Full Name

    azurocidin 1

  • Overview

    Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Jul 2008]

  • Synonyms

    AZU1;azurocidin 1;AZU;HBP;NAZC;AZAMP;CAP37;HUMAZUR;azurocidin;neutrophil azurocidin;heparin-binding protein;cationic antimicrobial protein 37;cationic antimicrobial protein CAP37

Recombinant Proteins

  • Human
  • HEK293
  • Wheat Germ
  • E.coli
  • Human Cell
  • HEK293 cells
  • In Vitro Cell Free System
  • Mammalian cells
  • Human Neutrophil
  • Insect Cells
  • His
  • GST
  • Non
Cat.# Product name Source (Host) Species Tag Protein Length Price
AZU1-588H Recombinant Human AZU1 protein, His-tagged HEK293 Human His Ile27-Pro250
AZU1-1055H Recombinant Human AZU1 protein, GST-tagged Wheat Germ Human GST
AZU1-6989H Recombinant Human AZU1 protein, His-tagged E.coli Human His Pro23~Gly247
AZU1-3083HCL Recombinant Human AZU1 cell lysate Human Cell Human Non
AZU1-0045H Recombinant Human AZU1 Protein HEK293 cells Human
AZU1-0724H Recombinant Human AZU1 Protein (Pro23-Gly247), His tagged E.coli Human His Pro23-Gly247
AZU1-094H Recombinant Human AZU1 Protein, His-tagged HEK293 Human His 251
AZU1-1303H Recombinant Human AZU1 protein, His-tagged HEK293 Human His 27-248aa
AZU1-1547HF Recombinant Full Length Human AZU1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 251 amino acids
AZU1-1594H Recombinant Human AZU1 Protein (Ile27-Pro250), C-His tagged Mammalian cells Human His Ile27-Pro250
AZU1-26565TH Native Human AZU1 Human Neutrophil Human Non 222 amino acids
AZU1-40H Native Human Azurocidin Human Neutrophil Human Non
AZU1-5024H Recombinant Human AZU1 Protein (Met1-R1036), C-His tagged Insect Cells Human His Met1-R1036

    Involved Pathway

    AZU1 involved in several pathways and played different roles in them. We selected most pathways AZU1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AZU1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    AZU1 has several biochemical functions, for example, heparan sulfate proteoglycan binding,heparin binding,peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AZU1 itself. We selected most functions AZU1 had, and list some proteins which have the same functions with AZU1. You can find most of the proteins on our site.

    Function Related Protein
    serine-type endopeptidase activity TMPRSS3,FURIN,KLK5,HPR,GZMC,C2,RHBDL3,PRSS54,Gzmd,DPP4
    protein binding EXD1,AKR1C1,IGF2BP3,RAPGEF4,PSMG2,SLA,STRA13,PI4KB,DUSP14,CBS
    toxic substance binding DSG1,NEFH,CHRNA7,ASS1,EPHX2,Alb,PHAX,A4GALT,H2-AB1,GUCY2C
    heparin binding SERPIND1,NELL2,PTPRF,FGF9,FGFR1A,CXCL6,FBLN7,CXCL13,CHRD,APOA5
    peptidase activity PLAUA,IHH,STAMBPA,HE2,CELA3B,USP9,CAPN2L,MCPT2,SPG7,TMPRSS13B
    heparan sulfate proteoglycan binding GPC1,GPC6,HPSE2,UBE4A,FST,GPC1B,GPC6A,SLIT2,GPC5A,COMP

    Interacting Protein

    AZU1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AZU1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AZU1.

    CLEC4G;dsdna_dcmdg:dcmdg;A2M

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