ATXN3L
-
Official Full Name
ATXN3L ataxin 3-like [ Homo sapiens ] -
Overview
This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease. -
Synonyms
ataxin 3-like;ATX3L;MJDL;EC 3.4.19.12;Machado-Joseph disease protein 1-like;EC 3.4.22;putative ataxin-3-like protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ATXN3L-10070H | Recombinant Human ATXN3L, GST-tagged | E.coli | Human | GST | 271-341a.a. | |
| ATXN3L-174H |
Active Recombinant Human ATXN3L, His-tagged
|
E.coli | Human | His | 1-355 a.a. |
|
| ATXN3L-203H |
Active Recombinant Human ATXN3L protein, His-tagged
|
Insect Cell | Human | His |
|
|
| ATXN3L-164H | Recombinant Human ATXN3L, His-tagged | E.coli | Human | His |
|
|
| ATXN3L-0373H | Recombinant Human ATXN3L Protein (D2-K355), Flag tagged | Insect Cell | Human | Flag | D2-K355 |
|
| ATXN3L-0374H | Recombinant Human ATXN3L Protein (D2-K355), His/Flag tagged | Insect Cell | Human | His&Flag | D2-K355 |
|
Involved Pathway
ATXN3L involved in several pathways and played different roles in them. We selected most pathways ATXN3L participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATXN3L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | DNAJC5GB,CUL1,CAPN2,HSPH1,SEC63,EIF2S1B,TXNDC5,RPN2,HERPUD1,EDEM3 |
Protein Function
ATXN3L has several biochemical functions, for example, RNA polymerase II regulatory region DNA binding,histone deacetylase activity,omega peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATXN3L itself. We selected most functions ATXN3L had, and list some proteins which have the same functions with ATXN3L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II regulatory region DNA binding | PPARG,NKX2-1,NPAS4,NCOA1,TXK |
| histone deacetylase activity | SIRT1,NACC2,HDAC5,HDAC7,HDAC6,SIRT2,MTA2,HDAC3,HDAC1,HDAC2 |
| ubiquitin-specific protease activity | OTUD4,USP30,JOSD2,OTUD6A,USP38,TNFAIP3,USP12,OTULIN,BRCC3,USP17L2 |
| omega peptidase activity | GGH,USP13,JOSD1,USP5,JOSD2,APEH,ATXN3,UCHL5,UCHL1 |
Interacting Protein
ATXN3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATXN3L here. Most of them are supplied by our site. Hope this information will be useful for your research of ATXN3L.
Resources
Related Services
Related Products
References
