ATP6V1D

  • Official Full Name

    ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D

  • Overview

    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c, c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein.

  • Synonyms

    ATP6V1D;ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D;ATP6M, ATPase, H+ transporting, lysosomal (vacuolar proton pump);V-type proton ATPase subunit D;VATD;VMA8;V-ATPase D subunit;V-ATPase subunit D;vacuolar H-ATPase subunit D;vacuolar p

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • Chicken
  • Zebrafish
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ATP6V1D-10045H Recombinant Human ATP, His-tagged E.coli Human His 1-247a.a.
ATP6V1D-1005H Recombinant Human ATP6V1D protein, GST-tagged Wheat Germ Human GST
ATP6V1D-2163M Recombinant Mouse ATP6V1D Protein Mammalian Cell Mouse His
ATP6V1D-468R Recombinant Rhesus monkey ATP6V1D Protein, His-tagged Mammalian Cell Rhesus macaque His
ATP6V1D-4840C Recombinant Chicken ATP6V1D Mammalian Cell Chicken His
ATP6V1D-7632Z Recombinant Zebrafish ATP6V1D Mammalian Cell Zebrafish His
ATP6V1D-50HCL Recombinant Human ATP6V1D lysate HEK293 Human Non
ATP6V1D-1284HF Recombinant Full Length Human ATP6V1D Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 247 amino acids
ATP6V1D-297R Recombinant Rhesus Macaque ATP6V1D Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
ATP6V1D-297R-B Recombinant Rhesus Macaque ATP6V1D Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ATP6V1D-879M Recombinant Mouse ATP6V1D Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ATP6V1D-879M-B Recombinant Mouse ATP6V1D Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ATP6V1D involved in several pathways and played different roles in them. We selected most pathways ATP6V1D participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP6V1D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rheumatoid arthritis IL1A,IL17A,Il23a; Il12b,TNFSF13,CXCL6,ITGB2,ATP6V1A,ATP6V0B,CCL20,TEK
    Epithelial cell signaling in Helicobacter pylori infection CXCR1,RAC1,ATP6V0D1,CXCL1,MAPK11,MAPK10,ATP6V1A,ATP6V1H,ATP6V1C2,LYN
    Synaptic vesicle cycle STX1A,SNAP25,CPLX4,SLC17A6,UNC13A,ATP6V0C,ATP6V1B2,ATP6V0D2,ATP6V0B,ATP6V1A
    Oxidative phosphorylation UQCRC1,ATP6AP2,NDUFB2,ATP5I,COX10,SDHA,UQCRB,ATP6AP1,COX7A2A,ATP5G3
    Phagosome MHC1UXA2,ATP6V0D2,SEC61A1,VAMP3,RAB5C,ATP6V1C1B,C3A.2,BLA,ACTB2,BLB2
    Vibrio cholerae infection PLCG1,ATP6V1C2,ATP6V1A,ATP6V0A2,ATP6V1E2,KDELR1,PRKACG,KDELR2,ATP6V0D2,ATP6V1G2
    Metabolic pathways PRIM2,DHRS13L1,NDST1,CYP26C1,PLCB2,ALOX5,GALT,AUH,SRM,ALDOCB
    Collecting duct acid secretion ATP6V0E2,SLC12A7,ATP6V0C,ATP6V1C2,ATP4A,ATP6V0A2,ATP6V1G2,Car2,ATP4B,ATP6V0A4

    Protein Function

    ATP6V1D has several biochemical functions, for example, ATPase activity, coupled to transmembrane movement of substances,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP6V1D itself. We selected most functions ATP6V1D had, and list some proteins which have the same functions with ATP6V1D. You can find most of the proteins on our site.

    Function Related Protein
    protein binding BOP1,SEC14L4,SOX17,ARMC9,PTPRJ,RBM4,FLOT1,FRA10AC1,EPS15,SERPINB8
    ATPase activity, coupled to transmembrane movement of substances ABCG5,ABCD4,ABCB1,ABCA1,ABCD3A,ABCA6,ABCC5,ABCA4,ABCG2,ABCB3L1

    Interacting Protein

    ATP6V1D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP6V1D here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP6V1D.

    VPS52;NR2F6;SMAD2;RRAGB;pi3p;MYC;MYH7;ATP6V1A;PSMC1;PPP2CA;CLTC;USP7;Tmed10;GOLT1B

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