ATP5O
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Official Full Name
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -
Overview
The protein encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance. -
Synonyms
ATP5O;ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit;ATP synthase subunit O, mitochondrial;ATPO;oligomycin sensitivity conferring protein;OSCP;mitochondrial;ATP synthase O subunit mitochondrial precursor;ATP synthase subunit O;ATPO_HUMAN;EC 3.6.3.14;Mitochondrial ATP synthase, O subunit;MS505;Oligomycin sensitivity conferral protein;OTTHUMP00000067745;human ATP synthase OSCP subunit
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
ATP5O involved in several pathways and played different roles in them. We selected most pathways ATP5O participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5O were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Parkinsons disease | NDUFB7,SLC25A5,NDUFC1,NDUFB6,NDUFA13,ATP5F1,UQCR10,mt-Atp8,MT-ND4,UBE2J2 |
| Metabolic pathways | ACOX2,GGPS1,ADH2-1,AMY2A5,CYP3A41A,GUSB,PLCD3,ATP5B,UGT1A6A,LIPT2 |
| Oxidative phosphorylation | ATP5F1,ATP6V1E2,NDUFA4L,ATP6V0A2B,NDUFV2,COX6B2,COX10,ATP6AP1,NDUFS3,PPA2 |
| Huntingtons disease | PPARGC1A,DNAH11,ITPR1,NDUFA4L2,CASP9,COX7B,COX8C,TFAM,POLR2G,NDUFA12 |
| Alzheimers disease | CAPN2,APH1C,NAE1,CALM4,ATP5E,GRIN1,AKR1C1,UQCRB,CYCS,CALML3 |
Protein Function
ATP5O has several biochemical functions, for example, contributes_to ATPase activity,drug binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5O itself. We selected most functions ATP5O had, and list some proteins which have the same functions with ATP5O. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| proton-transporting ATP synthase activity, rotational mechanism | ATP6V0C,ATP6AP1B,ATP5C1,ATP6AP1,ATP5E,ATP5B,ATP5A1 |
| drug binding | DAAM2,HTR2C,CHRNA2,DRD1,CHRNB4,DRD3,FSCN1,GPR30,DHFR,CHRM3 |
| transporter activity | AQP8A.1,SLC22A23,CLVS1,SLC2A15A,DYF-1,UCP3,KIF20A,FABP1B.1,TIMM9,SLC37A4A |
| contributes_to ATPase activity | SFRP5,ATP6V1H,ATP5E,ATP1A2,ATP1B1,ATP5B,PPP2R4,RUVBL2,ATP5J,ATP5C1 |
| protein binding | ADAM33,TSPAN4,TIMM50,EDARADD,SV2B,CSTF1,CDH23,OLFM4,LRRC4,ALG13 |
| transmembrane transporter activity | SV2C,SLC22A13,SLC17A9B,ATP5J,AQP1,SLC22A7A,SLC2A11B,SLC22A17,SLC17A9,SLC22A1 |
Interacting Protein
ATP5O has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5O here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5O.
PNMA1;KRT13;NDC80;ZBTB14;KRT15;NT5C2;TRIP6
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