ATP2B4

  • Official Full Name

    ATPase, Ca++ transporting, plasma membrane 4

  • Overview

    Plasma membrane calcium-transporting ATPase 4 is an enzyme that in humans is encoded by the ATP2B4 gene.

  • Synonyms

    ATP2B4;ATPase, Ca++ transporting, plasma membrane 4;plasma membrane calcium-transporting ATPase 4;AT2B4_HUMAN;ATP2B2;ATPase Ca++ transporting plasma membrane 4;Cation transporting ATPase;DKFZp686G08106;DKFZp686M088;Matrix remodelling associated 1;Matrix remodelling associated protein 1;Matrix-remodeling-associated protein 1;MXRA 1;MXRA1;OTTHUMP00000034088;OTTHUMP00000034089;Plasma membrane calcium ATPase 4;Plasma membrane calcium ATPase isoform 4;Plasma membrane calcium pump isoform 4;Plasma membrane calcium transporting ATPase 4;PMCA 4;PMCA4;PMCA4b;PMCA4x;Sarcolemmal calcium pump;ATPase, Ca++ transporting, plasma membrane 4 ATP synthase, H+ transporting, mitochondrial F1

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Zebrafish
  • Rat
  • Mouse
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293T
  • HEK293
  • His
  • Non
  • GST
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ATP2B4-2588H Recombinant Human ATP2B4 protein, His-tagged E.coli Human His 281-345 aa
ATP2B4-27795TH Recombinant Human ATP2B4 Wheat Germ Human Non 92 amino acids
ATP2B4-451R Recombinant Rhesus monkey ATP2B4 Protein, His-tagged Mammalian Cell Rhesus macaque His
ATP2B4-4741Z Recombinant Zebrafish ATP2B4 Mammalian Cell Zebrafish His
ATP2B4-864R Recombinant Rat ATP2B4 Protein Mammalian Cell Rat His
ATP2B4-973H Recombinant Human ATP2B4 protein, GST-tagged Wheat Germ Human GST
Atp2b4-1767M Recombinant Mouse Atp2b4 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
ATP2B4-280R Recombinant Rhesus Macaque ATP2B4 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
ATP2B4-280R-B Recombinant Rhesus Macaque ATP2B4 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ATP2B4-2945H Recombinant Human ATP2B4 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
ATP2B4-301117H Recombinant Human ATP2B4 protein, GST-tagged E.coli Human GST Gly281-Pro345
ATP2B4-520R Recombinant Rat ATP2B4 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
ATP2B4-520R-B Recombinant Rat ATP2B4 Protein Pre-coupled Magnetic Beads HEK293 Rat
ATP2B4-6544H Recombinant Human ATP2B4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
ATP2B4-865R Recombinant Rat ATP2B4 Protein, His-tagged E.coli Rat His Pro1018~Val1203

    Involved Pathway

    ATP2B4 involved in several pathways and played different roles in them. We selected most pathways ATP2B4 participated on our site, such as Calcium signaling pathway,cGMP-PKG signaling pathway,cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2B4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway GNAI3,GNA11,BAD,MAPK3,GNAQ,ATP1B1,AGTR1B,PRKCE,BNP,PLN
    Pancreatic secretion PLA2G12A,KCNQ1,RAP1B,AMY2A,PRKCA,RAB8A,PRSS1,RYR2,PLCB4,ATP1B1
    Adrenergic signaling in cardiomyocytes ADCY2B,CAMK2D1,PPP2R3A,ADCY1B,CACNG7A,ADRB3A,ADRB3B,CACNA2D1,PPP2R1B,AGTR1A
    Salivary secretion Adcy4,CST4,PLCB3,PLCB2,CALM2,ITPR1,SLC9A1,ATP1A4,BEST2,PRKCB
    Calcium signaling pathway HTR7,PDE1C,SPHK2,GNA15.1,CCKBR,CHRM5A,MLCK2,PLCD4,SLC8A2B,SLC25A5
    cAMP signaling pathway PPP1CA,NPY1R,AMH,MC2R,PIK3R2,ATP1B4,PLN,ATP1A4,EP300,PPARA

    Protein Function

    ATP2B4 has several biochemical functions, for example, ATP binding,PDZ domain binding,calcium-transporting ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2B4 itself. We selected most functions ATP2B4 had, and list some proteins which have the same functions with ATP2B4. You can find most of the proteins on our site.

    Function Related Protein
    scaffold protein binding MAP2K2,KRT15,CACNA1G,KCNA5,PARK7,NLGN4X,LRP4,VIM,P2RY1,CASP8
    calcium-transporting ATPase activity ATP2A1L,ATP2A3,ATP2B1A,ATP2B1,ATP2A2A,ATP2B3B,ATP2B1B,ATP2C1,ATP2A1,ATP2B2
    nitric-oxide synthase binding SCN5A,CALM3,ACTB,DNM2,DNM3,CALM2,CDH2,CAMK2D,SLC14A2,NOS1AP
    protein phosphatase 2B binding SOD1,AKAP1,PPP3CB,AKAP5,MYOZ2,BAD,SLC9A1
    contributes_to sodium channel regulator activity SNTA1
    metal ion binding PDE8B,SP8B,HIC1,PDE12,ZNF728,BGLAP2,ZNF497,HRG,FDX1L,ATP1A3
    calmodulin binding IQGAP3,PDE1A,KCNQ1,SMTNL1,CAMK1,PATE4,CAMKVB,NRGNA,C2orf62,MAPKAPK5
    ATP binding DDX39A,P2RX3A,PRKCH,CCT4,SIK2A,CDK10,C22orf28,DAPK3,DHX16,MAST4
    PDZ domain binding SLC22A5,GNG12,TBC1D10A,PARK2,PSEN1,TGFBR3,GRIK2,GJA1,PLEKHA1,NSF

    Interacting Protein

    ATP2B4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2B4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2B4.

    Nos1;CALCA;STIM1;Nos1;15-deoxy-delta(12,14;EGFR;1C;CDK7;YWHAE

    Resources

    References

    • Brandenburger, T; Strehler, EE; et al. Switch of PMCA4 Splice Variants in Bovine Epididymis Results in Altered Isoform Expression during Functional Sperm Maturation. JOURNAL OF BIOLOGICAL CHEMISTRY 286:7938-7946(2011).
    • Mangialavori, I; Giraldo, AMV; et al. A New Conformation in Sarcoplasmic Reticulum Calcium Pump and Plasma Membrane Ca2+ Pumps Revealed by a Photoactivatable Phospholipidic Probe. JOURNAL OF BIOLOGICAL CHEMISTRY 284:4823-4828(2009).

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