ATP12A
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Official Full Name
ATPase, H+/K+ transporting, nongastric, alpha polypeptide -
Overview
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ATP12A;ATPase, H+/K+ transporting, nongastric, alpha polypeptide;ATP1AL1, ATPase, Na+/K+ transporting, alpha polypeptide like 1;potassium-transporting ATPase alpha chain 2;ATPase;Na+K+ transporting;alpha 1 polypeptide like;non gastric H(+)/K(+) ATPase alpha subunit;potassium transporting ATPase alpha chain 2;proton pump;sodium/potassium ATPase;alpha polypeptide like;ATP1AL1;ATPase H+/K+ transporting nongastric alpha polypeptide;ATPase Na+K+ transporting alpha-1 polypeptide-like;Hydrogen/potassium-exchanging ATPase 12A;Non-gastric H(+)/K(+) ATPase subunit alpha;Sodium/potassium ATPase alpha polypeptide-like;non-gastric H(+)/K(+) ATPase alpha subunit;ATPase, Na+/K+ transporting, alpha polypeptide-like 1
Recombinant Proteins
- Mouse
- Chicken
- Rat
- Human
- Mammalian Cell
- Wheat Germ
- HEK293
- E.coli
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ATP12A-2107M | Recombinant Mouse ATP12A Protein | Mammalian Cell | Mouse | His |
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| ATP12A-2598C | Recombinant Chicken ATP12A | Mammalian Cell | Chicken | His |
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| ATP12A-851R | Recombinant Rat ATP12A Protein | Mammalian Cell | Rat | His |
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| ATP12A-961H | Recombinant Human ATP12A protein, GST-tagged | Wheat Germ | Human | GST |
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| ATP12A-8614HCL | Recombinant Human ATP12A 293 Cell Lysate | HEK293 | Human | Non |
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| ATP12A-263H | Recombinant Human ATP12A Protein, His-tagged | E.coli | Human | His | Met1-Pro102 |
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| ATP12A-507R | Recombinant Rat ATP12A Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ATP12A-507R-B | Recombinant Rat ATP12A Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ATP12A-844M | Recombinant Mouse ATP12A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ATP12A-844M-B | Recombinant Mouse ATP12A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ATP12A involved in several pathways and played different roles in them. We selected most pathways ATP12A participated on our site, such as Oxidative phosphorylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP12A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Oxidative phosphorylation | ATP6AP1,ATP6V0E,ATP4B,UQCR11,ATP6V0C,NDUFA11,NDUFS8A,NDUFA4L2,UQCRH,UQCRQ |
Protein Function
ATP12A has several biochemical functions, for example, ATP binding,hydrogen:potassium-exchanging ATPase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP12A itself. We selected most functions ATP12A had, and list some proteins which have the same functions with ATP12A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sodium:potassium-exchanging ATPase activity | ATP1A1A.3,ATP1A1B,ATP1A1,ATP1A3A,ATP1A1A.1,ATP4A,ATP1A3B,ATP1A1A.4,ATP1A2A,FXYD2 |
| hydrogen:potassium-exchanging ATPase activity | ATP4B,ATP4A,ATP6V1E1B |
| ATP binding | ATP8B3,MAP4K1,TIMM44,BMPR1BB,TNK1,PAK1,IARS2,PI4KA,ACSM3,ABCD2 |
| metal ion binding | BCL11BA,SALL3B,ADIPOR2,ZHX1,ZFYVE9,SOBPB,RREB1,PVALB6,COL5A1,SLC8A1 |
Interacting Protein
ATP12A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP12A here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP12A.
NPY;GNAI3;PPIB;MME
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