ATL1

  • Official Full Name

    atlastin GTPase 1
  • Overview

    The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
  • Synonyms

    ATL1;atlastin GTPase 1;spastic paraplegia 3A (autosomal dominant) , SPG3, SPG3A;atlastin-1;AD FSP;atlastin;FSP1;Atlastin1;Brain specific GTP binding protein;GBP3;SPG 3A;SPG3;GBP-3;hGBP3;GTP-binding protein 3;guanylate-binding protein 3;spastic paraplegia 3 protein A;brain-specific GTP-binding protein;guanine nucleotide-binding protein 3;HSN1D;SPG3A;AD-FSP

Recombinant Proteins

  • Human
  • Mouse
  • Cynomolgus
  • Rhesus macaque
  • Zebrafish
  • Rat
  • Macaca fascicularis
  • Mus musculus
  • Pongo Abelii
  • Bovine
  • Arabidopsis thaliana
  • Insect Cells
  • E.coli
  • Mammalian Cell
  • Insect Cell
  • HEK293T
  • HEK293
  • E.coli expression system
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ATL1-3333H Recombinant Human ATL1 protein, GST-tagged Insect Cells Human GST Met1-Thr447
ATL1-9984H Recombinant Human ATL1, GST-tagged E.coli Human GST N-term-350a.a.
ATL1-2091M Recombinant Mouse ATL1 Protein Mammalian Cell Mouse His
ATL1-319C Recombinant Cynomolgus ATL1 Protein, His-tagged Mammalian Cell Cynomolgus His
ATL1-445R Recombinant Rhesus monkey ATL1 Protein, His-tagged Mammalian Cell Rhesus macaque His
ATL1-7377Z Recombinant Zebrafish ATL1 Mammalian Cell Zebrafish His
ATL1-848R Recombinant Rat ATL1 Protein Mammalian Cell Rat His
ATL1-669HCL Recombinant Human ATL1 cell lysate Insect Cell Human Non
ATL1-1062H Recombinant Human ATL1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Atl1-1764M Recombinant Mouse Atl1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
ATL1-274R Recombinant Rhesus Macaque ATL1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
ATL1-274R-B Recombinant Rhesus Macaque ATL1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ATL1-2943H Recombinant Human ATL1 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
ATL1-504R Recombinant Rat ATL1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
ATL1-504R-B Recombinant Rat ATL1 Protein Pre-coupled Magnetic Beads HEK293 Rat
ATL1-69C Recombinant Cynomolgus Monkey ATL1 Protein, His (Fc)-Avi-tagged HEK293 Cynomolgus His&Fc&Avi
ATL1-69C-B Recombinant Cynomolgus Monkey ATL1 Protein Pre-coupled Magnetic Beads HEK293 Cynomolgus
ATL1-832M Recombinant Mouse ATL1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ATL1-832M-B Recombinant Mouse ATL1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
RFL12079RF Recombinant Full Length Rat Atlastin-1(Atl1) Protein, His-Tagged E.coli expression system Rat His Full L. Full Length (1-558)
RFL18370MF Recombinant Full Length Macaca Fascicularis Atlastin-1(Atl1) Protein, His-Tagged E.coli expression system Macaca fascicularis His Full L. Full Length (1-558)
RFL20099MF Recombinant Full Length Mouse Atlastin-1(Atl1) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-558)
RFL29280PF Recombinant Full Length Pongo Abelii Atlastin-1(Atl1) Protein, His-Tagged E.coli expression system Pongo Abelii His Full L. Full Length (1-558)
RFL32288HF Recombinant Full Length Human Atlastin-1(Atl1) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-558)
RFL34995BF Recombinant Full Length Bovine Atlastin-1(Atl1) Protein, His-Tagged E.coli expression system Bovine His Full L. Full Length (1-558)
RFL79AF Recombinant Full Length Arabidopsis Thaliana Ring-H2 Finger Protein Atl1(Atl1) Protein, His-Tagged E.coli expression system Arabidopsis thaliana His Full L. Full Length (1-381)

    Involved Pathway

    ATL1 involved in several pathways and played different roles in them. We selected most pathways ATL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ATL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    ATL1 has several biochemical functions, for example, GTP binding,GTPase activity,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATL1 itself. We selected most functions ATL1 had, and list some proteins which have the same functions with ATL1. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activity RAB5AB,TUBD1,RAB2B,GNAT3,LRRK2,ARHGAP5,RAB10,RND2,IFT27,IRGF1
    protein binding FES,HNRNPC,WBSCR27,MTF1,TINF2,U2AF1,STUB1,CEBPB,DUSP15,NFYB
    GTP binding MFN2,RNGTT,RAB3AB,RASL11A,RAB27A,EHD1,GPN2,RAB27B,RAB42A,RAB14L
    identical protein binding MPST,TGFB3,COL1A2,KCNRG,MUL1A,CREBZF,KRTAP10-5,BCAT1,MCIN,PYDC3

    Interacting Protein

    ATL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATL1.

    TMED2;Rtn3;Reep5;Rtn4;RTN4;TMED10;TMED9

    Resources

    References

    • Peng, Y; Bo, L; et al. Interaction between antigen presenting cells and autoreactive T cells derived from BXSB mice with murine lupus. CELL RESEARCH 17:556-564(2007).
    • Han, SH; Li, B; et al. Isolation and functional analysis of autoreactive T cells from BXSB mice with murine lupus. JOURNAL OF AUTOIMMUNITY 19:45-54(2002).

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