ART4
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Official Full Name
ADP-ribosyltransferase 4 (Dombrock blood group) -
Overview
This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. -
Synonyms
ART4;ADP-ribosyltransferase 4 (Dombrock blood group);ADP ribosyltransferase 4 , ADP ribosyltransferase 4 (DO blood group) , DO, Dombrock blood group;ecto-ADP-ribosyltransferase 4;CD297;DOK1;ADP ribosyltransferase 4 (DO blood group);ADP ribosyltransferase 4 (Dombrock blood group);ADP ribosyltransferase 4;ART 4;CD297 antigen;DO;Dombrock blood group carrier molecule;Ecto ADP ribosyltransferase 4;Mono ADP ribosyltransferase 4;Mono(ADP ribosyl)transferase 4;NAD(P)(+) arginine ADP ribosyltransferase 4;mono-ADP-ribosyltransferase 4;mono(ADP-ribosyl)transferase 4;ADP-ribosyltransferase 4 (DO blood group);NAD(P)(+)--arginine ADP-ribosyltransferase 4
Recombinant Proteins
- Human
- Cynomolgus
- Chicken
- Rat
- Mouse
- E.coli
- Human Cell
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- Mammalian cells
- His
- Fc
- His&T7
- GST
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ART4-3374H | Recombinant Human ART4 protein, His-tagged | E.coli | Human | His | 47-285 aa | |
| ART4-140C | Recombinant Cynomolgus ART4, Fc tagged | Human Cell | Cynomolgus | Fc | 31-300 a.a. |
|
| ART4-141C | Recombinant Cynomolgus ART4, His tagged | Human Cell | Cynomolgus | Fc | 31-300 a.a. |
|
| ART4-3890C | Recombinant Chicken ART4 | Mammalian Cell | Chicken | His |
|
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| Art4-716R | Recombinant Rat Art4 protein, His & T7-tagged | E.coli | Rat | His&T7 | Tyr51~Cys275 |
|
| Art4-7420M | Recombinant Mouse Art4 protein, hFc-tagged | HEK293 | Mouse | Fc | Met1-Lys263 |
|
| ART4-870H | Recombinant Human ART4 protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| Art4-8800R | Recombinant Rat Art4, His tagged | Human Cell | Rat | His | 1-269 a.a. |
|
| ART4-960M | Recombinant Mouse ART4 Protein, His-tagged | HEK293 | Mouse | His | 1-263 a.a. |
|
| ART4-1194RCL | Recombinant Rat ART4 cell lysate | Human Cell | Rat | Non |
|
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| ART4-1541MCL | Recombinant Mouse ART4 cell lysate | Human Cell | Mouse | Non |
|
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| ART4-925CCL | Recombinant Cynomolgus ART4 cell lysate | Human Cell | Cynomolgus | Non |
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| ART4-1019HF | Recombinant Full Length Human ART4 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 314 amino acids |
|
| ART4-101H | Recombinant Human ART4 Protein, His-tagged | E.coli | Human | His |
|
|
| ART4-301319H | Recombinant Human ART4 protein, GST-tagged | E.coli | Human | GST | Met1-Gly60 |
|
| ART4-4528H | Recombinant Human ART4 Protein (Met1-Val314), C-His tagged | Mammalian cells | Human | His | Met1-Val314 |
|
Involved Pathway
ART4 involved in several pathways and played different roles in them. We selected most pathways ART4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ART4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ART4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ART4 itself. We selected most functions ART4 had, and list some proteins which have the same functions with ART4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ART4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ART4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ART4.
Resources
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References
- de Coulgeans, CD; Silvy, M; et al. Synonymous nucleotide polymorphisms influence Dombrock blood group protein expression in K562 cells. BRITISH JOURNAL OF HAEMATOLOGY 164:131-141(2014).
- Westhoff, C; Vege, S; et al. A DOB allele encoding an amino acid substitution (Phe62Ser) resulting in a Dombrock null phenotype. TRANSFUSION 47:1356-1362(2007).
