ARPP19
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Official Full Name
ARPP19 cAMP-regulated phosphoprotein, 19kDa [ Homo sapiens ] -
Overview
The 19-kD cAMP-regulated phosphoprotein plays a role in regulating mitosis by inhibiting protein phosphatase-2A (PP2A; see MIM 176915) (summary by Gharbi-Ayachi et al., 2010 [PubMed 21164014]). -
Synonyms
ARP19;ARPP-16;ARPP-19;ARPP16;ARPP19;cAMP-regulated phosphoprotein 19;FLJ41622;cyclic AMP phosphoprotein, 19 kD;ENSAL
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
ARPP19 involved in several pathways and played different roles in them. We selected most pathways ARPP19 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARPP19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Mitotic Prophase | TMEM188,VRK1,NCAPH2,MASTL,CTDNEP1A,ARPP19A,DULLARD,CTDNEP1B,ENSAA,SET |
MASTL Facilitates Mitotic Progression | ARPP19B,ENSAA,ENSAB,ARPP19A,ENSA,MASTL |
M Phase | CENPQ,CENPC1,STAG2,CTDNEP1A,CENPP,PMF1,CNEP1R1,KIF2A,SET,CENPK |
Cell Cycle, Mitotic | NCAPG2,NCAPH2,NUP50,CCP110,NIPBLA,HIST2H3C,CDKN2B,NDEL1A,SMC4,CENPK |
Cell cycle | BLZF1,DNA2,CENPP,VRK1,CDCA5,MCM3,NUDC,CDC45,RAD50,SGOL1 |
Protein Function
ARPP19 has several biochemical functions, for example, phosphatase inhibitor activity,potassium channel regulator activity,protein phosphatase 2A binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARPP19 itself. We selected most functions ARPP19 had, and list some proteins which have the same functions with ARPP19. You can find most of the proteins on our site.
Function | Related Protein |
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potassium channel regulator activity | ANK2,PIAS3,DRD2,KCNAB3,KCNAB2,ARPP19A,ADRB2,SGK3,DLG1,KCNMB4 |
phosphatase inhibitor activity | ENSA,TESC,URI1,ENSAA,ANP32E |
protein phosphatase type 2A regulator activity | PPP2R2C,PPP2R1A,PPP2R2CA,PPP2R3A,PPP2R5B,PPP2R2B,PPP2R2BB,PPP2R1B,IGBP1,EIF2AK2 |
receptor binding | HMGCL,PGR,GDNF,FRK,SRMS,ANXA1,WIPI1,GNPAT,TNFSF13,CDH5 |
protein phosphatase inhibitor activity | PPP1R10,PPP1R14C,PHACTR1,SAG,PPP1R9B,DYSFIP1,PPP1R14B,PPP1R14D,GLC8,LMTK2 |
protein phosphatase 2A binding | GRIN3A,BCL2,RPS6KB1,TP53,CTTNBP2NL,ENSAA,ANKLE2,TRP53,FOXO1,STRN |
Interacting Protein
ARPP19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARPP19 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARPP19.
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