ARL13B

  • Official Full Name

    ADP-ribosylation factor-like 13B

  • Overview

    This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.

  • Synonyms

    ARL13B;ADP-ribosylation factor-like 13B;ADP ribosylation factor like 2 like 1 , ARL2L1;ADP-ribosylation factor-like protein 13B;DKFZp761H079;JBTS8;ADP ribosylation factor like 13B;ADP ribosylation factor like 2 like 1;ARL2L1;ARL2-like protein 1;ADP-ribosylation factor-like 2-like 1

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • HEK293T
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ARL13B-9851H Recombinant Human ARL13B, GST-tagged E.coli Human GST 1-321a.a.
ARL13B-1923M Recombinant Mouse ARL13B Protein Mammalian Cell Mouse His
ARL13B-805H Recombinant Human ARL13B protein, GST-tagged Wheat Germ Human GST
ARL13B-9543Z Recombinant Zebrafish ARL13B Mammalian Cell Zebrafish His
ARL13B-8720HCL Recombinant Human ARL13B 293 Cell Lysate HEK293 Human Non
ARL13B-8721HCL Recombinant Human ARL13B 293 Cell Lysate HEK293 Human Non
Arl13b-1703M Recombinant Mouse Arl13b Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
ARL13B-2385H Recombinant Human ARL13B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
ARL13B-717M Recombinant Mouse ARL13B Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ARL13B-717M-B Recombinant Mouse ARL13B Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ARL13B involved in several pathways and played different roles in them. We selected most pathways ARL13B participated on our site, such as ARL13B-mediated ciliary trafficking of INPP5E,Assembly of the primary cilium,Cargo trafficking to the periciliary membrane, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL13B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cargo trafficking to the periciliary membrane RHOL,BBS2,SSTR3,SETD6,EXOC5,CCT4,TTC8,RP2,CNGA2,EXOC8
    Organelle biogenesis and maintenance MRRF,EXOC3,CNGA2,RAB3IP,ARF4,GABPA,IFT43,SCLT1,CCDC123,NPHP4
    Assembly of the primary cilium EXOC1,CEP97,TUBB4A,CEP89,LZTFL1,BBS4,TUBB4B,SDCCAG8,CNGA5,NINL

    Protein Function

    ARL13B has several biochemical functions, for example, GTP binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL13B itself. We selected most functions ARL13B had, and list some proteins which have the same functions with ARL13B. You can find most of the proteins on our site.

    Function Related Protein
    protein binding PDE3B,ATP6V0A2,SOX14,RING1,KRTAP3-2,FBXO28,BAG6,CENPJ,ZBTB6,GFAP
    GTP binding EHD2,ACSM1,MXB,SEPT5B,GNAO1B,RAB5B,GTPBP10,EHD3,RAB13,RAB7B

    Interacting Protein

    ARL13B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL13B here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL13B.

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All ARL13B Products

    Required fields are marked with *

    My Review for All ARL13B Products

    Required fields are marked with *