ARHGEF16

  • Official Full Name

    Rho guanine nucleotide exchange factor (GEF) 16

  • Overview

    Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions.

  • Synonyms

    ARHGEF16;Rho guanine nucleotide exchange factor (GEF) 16;rho guanine nucleotide exchange factor 16;GEF16;NBR;putative neuroblastoma protein;ARHGEF 16;Rho guanine exchange factor (GEF) 16;ephexin-4

Recombinant Proteins

  • Mouse
  • Human
  • Zebrafish
  • Mammalian Cell
  • E.coli
  • Wheat Germ
  • In Vitro Cell Free System
  • HEK293
  • His
  • T7
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ARHGEF16-1891M Recombinant Mouse ARHGEF16 Protein Mammalian Cell Mouse His
ARHGEF16-2984H Recombinant Human ARHGEF16, T7-tagged E.coli Human T7 1-421 a.a.
ARHGEF16-6671Z Recombinant Zebrafish ARHGEF16 Mammalian Cell Zebrafish His
ARHGEF16-782H Recombinant Human ARHGEF16 protein, GST-tagged Wheat Germ Human GST
ARHGEF16-117HCL Recombinant Human ARHGEF16 cell lysate Human Non
ARHGEF16-1226HF Recombinant Full Length Human ARHGEF16 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 421 amino acids
ARHGEF16-2696H Recombinant Human ARHGEF16 Protein, His-tagged E.coli Human His
ARHGEF16-692M Recombinant Mouse ARHGEF16 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ARHGEF16-692M-B Recombinant Mouse ARHGEF16 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ARHGEF16 involved in several pathways and played different roles in them. We selected most pathways ARHGEF16 participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE,G alpha (12/13) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGEF16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rho GTPase cycle ARHGEF3,ARHGAP10,RHOT1A,CHN2,FGD2,ARHGAP17A,ARHGAP25,DLC1,ARHGAP8,NET1
    Signaling by GPCR ADCYAP1B,NMBB,RGS14,GPRC6A,GPR37L1,GPR39,CCL35.1,RGS18,FGD2,ARHGEF17
    Signaling by Rho GTPases TAGAP1,TAGAP,ARHGAP23,FAM13B,ARHGAP22,ARHGAP19,ARHGAP24,RHPN1,ARHGAP8,NOXO1
    G alpha (12/13) signalling events GNA13,ARHGAP4A,DCLRE1B,ARHGEF1A,KALRN,FGD4,ARHGAP4,KALRNB,ARHGEF9,NET1
    Signal Transduction IRBP,HHAT,PRDM4,BCL9,EVC2,UTS2D,ACKR4,TJP2B,NRP2B,GMIP
    NRAGE signals death through JNK ARHGAP4,FGD4A,ABR,ARHGEF1A,ARHGEF3,ECT2,ARHGEF18A,ARHGAP4A,PLEKHG2,ARHGEF9
    GPCR downstream signaling S1PR5B,OXER1,ARHGEF1A,CNR2,ARHGEF18A,GPR18,OPN1LW2,CXCL13,CCL35.2,ARHGEF1B
    Cell death signalling via NRAGE, NRIF and NADE OBSCN,PLEKHG2,ARHGEF18,ARHGEF17,CASP2,KALRN,ARHGAP4A,NET1,AKAP13,AATF

    Protein Function

    ARHGEF16 has several biochemical functions, for example, PDZ domain binding,Rho GTPase binding,Rho guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGEF16 itself. We selected most functions ARHGEF16 had, and list some proteins which have the same functions with ARHGEF16. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CC2D2A,NCF2,ID1,PIK3R1,MSH6,BEND3,PHF17,ZBED4,RHOC,RND1
    receptor tyrosine kinase binding PIK3R2,GNB2L1,PITPNM3,MYOC,ZNF259,ANGPT2,LRP4,PTPN2,DOCK4,PTPN1
    Rho guanyl-nucleotide exchange factor activity ALS2CL,DCLRE1B,ARHGEF7B,ARHGEF17,ARHGEF2,TIAM2,FGD6,RASGRF2B,ARHGEF6,VAV3B
    PDZ domain binding EXOC4,ATP2B3A,SLC26A6,SLC9A3R2,CIT,PROSAPIP1,FZD1,CFTR,PTENB,LIN7C
    Rho GTPase binding ROCK2B,DIAP1,DOCK9,CDC42BPB,ANTXR2A,PARD6A,DAAM1,LRRK2,DAAM1B,ROCK2A

    Interacting Protein

    ARHGEF16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGEF16 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGEF16.

    TFG;MAPK1IP1L;TFG;SFN;YWHAG;YWHAZ

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