ARHGDIG
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Official Full Name
Rho GDP dissociation inhibitor (GDI) gamma -
Overview
The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843). -
Synonyms
ARHGDIG;Rho GDP dissociation inhibitor (GDI) gamma;rho GDP-dissociation inhibitor 3;RhoGDI gamma;RHOGDI 3;GDIR3_HUMAN;OTTHUMP00000067353;OTTHUMP00000194914;Rho GDI 3;Rho GDI gamma;Rho GDP dissociation inhibitor 3;Rho GDP dissociation inhibitor gamma;Rho-GDI gamma;RHOGDI3;OTTHUMP00000067352;RHOGDI-3
Recombinant Proteins
- Human
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ARHGDIG-9830H | Recombinant Human ARHGDIG, His-tagged | E.coli | Human | His | 1-225a.a. | |
| ARHGDIG-11376Z | Recombinant Zebrafish ARHGDIG | Mammalian Cell | Zebrafish | His |
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| ARHGDIG-617H | Recombinant Human ARHGDIG | Mammalian Cell | Human | His |
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| ARHGDIG-776H | Recombinant Human ARHGDIG protein, GST-tagged | Wheat Germ | Human | GST |
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| ARHGDIG-115HCL | Recombinant Human ARHGDIG cell lysate | Human | Non |
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| ARHGDIG-1189HF | Recombinant Full Length Human ARHGDIG Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 225 amino acids |
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| ARHGDIG-2495H | Recombinant Human ARHGDIG Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| ARHGDIG-2495H-B | Recombinant Human ARHGDIG Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| ARHGDIG-26234TH | Recombinant Human ARHGDIG | Wheat Germ | Human | Non | 225 amino acids |
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| ARHGDIG-26HF | Recombinant Full Length Human ARHGDIG Protein | In Vitro Cell Free System | Human | Full L. 225 amino acids |
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Involved Pathway
ARHGDIG involved in several pathways and played different roles in them. We selected most pathways ARHGDIG participated on our site, such as Neurotrophin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGDIG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neurotrophin signaling pathway | MAP2K7,IRAK1,SHC3,KRAS,HRAS,NTRK2,RPS6KA5,RAP1B,Fasl,PIK3R1 |
Protein Function
ARHGDIG has several biochemical functions, for example, GTPase activator activity,Rho GDP-dissociation inhibitor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGDIG itself. We selected most functions ARHGDIG had, and list some proteins which have the same functions with ARHGDIG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Rho GDP-dissociation inhibitor activity | ARHGDIA,ARHGDIB |
| GTPase activator activity | ARFGAP1,ARHGEF12,SMAP2,RIN3,ELMOD2,ALDH1A1,RGS19,RAB3GAP2,ARHGEF19,RANGAP1B |
| protein binding | P2RX4,CTBP2,FGF1,ARL11,NFKBIL1,NHLH2,PLCE1,SRPK2,FBXO11,MED31 |
Interacting Protein
ARHGDIG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGDIG here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGDIG.
CEP170P1;KXD1
Resources
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References
- Wang, J; Li, X; et al. Overexpression of Rho-GDP-Dissociation Inhibitor-gamma Inhibits Migration of Neural Stem Cells. JOURNAL OF NEUROSCIENCE RESEARCH 91:1394-1401(2013).
- Wang, J; Cheng, H; et al. Regulation of Neural Stem Cell Differentiation by Transcription Factors HNF4-1 and MAZ-1. MOLECULAR NEUROBIOLOGY 47:228-240(2013).
