AQP6
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Official Full Name
aquaporin 6, kidney specific -
Overview
The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. -
Synonyms
AQP6;aquaporin 6, kidney specific;AQP2L;aquaporin-6;hKID;AQP-6;kidney-specific aquaporin;aquaporin-6, kidney specific;aquaporin 2-like, kidney specific;KID
Recombinant Proteins
- Human
- Mouse
- Rat
- Mus musculus
- Milnesium tardigradum (Water bear) (Tardigrade)
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AQP6-2680H | Recombinant Human AQP6 protein, His-tagged | E.coli | Human | His | 221 - 282 aa | |
| AQP6-1825M | Recombinant Mouse AQP6 Protein | Mammalian Cell | Mouse | His |
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| AQP6-740R | Recombinant Rat AQP6 Protein | Mammalian Cell | Rat | His |
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| AQP6-8766HCL | Recombinant Human AQP6 293 Cell Lysate | HEK293 | Human | Non |
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| AQP6-301468H | Recombinant Human AQP6 protein, GST-tagged | E.coli | Human | GST | Met221-Val282 |
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| AQP6-396R | Recombinant Rat AQP6 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| AQP6-396R-B | Recombinant Rat AQP6 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| AQP6-651M | Recombinant Mouse AQP6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| AQP6-651M-B | Recombinant Mouse AQP6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RFL17928HF | Recombinant Full Length Human Aquaporin-6(Aqp6) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-282) |
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| RFL27637RF | Recombinant Full Length Rat Aquaporin-6(Aqp6) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-276) |
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| RFL8222MF | Recombinant Full Length Mouse Aquaporin-6(Aqp6) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-293) |
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| RFL9235MF | Recombinant Full Length Milnesium Tardigradum Aquaporin-6(Aqp6) Protein, Tag-Free | E.coli expression system | Milnesium tardigradum (Water bear) (Tardigrade) | Non | Full L. Full Length (1-285) |
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Involved Pathway
AQP6 involved in several pathways and played different roles in them. We selected most pathways AQP6 participated on our site, such as Aquaporin-mediated transport,Passive transport by Aquaporins,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with AQP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Aquaporin-mediated transport | AQP10A,GNB5A,MIPB,ADCY8,GNB3A,AQP1A.2,GNB5,AQP1A.1,MIP,AQP9B |
| Transmembrane transport of small molecules | GLRBA,APOD,SLC9A10,MIP,NIPA1,SLC26A3.1,TRPC4AP,ANO10,MMGT1,SLC43A1A |
| Passive transport by Aquaporins | AQP8A.1,AQP11,AQP10B,AQP10A,AQP3B,AQP1A.2,AQP9B,AQP1A.1,MIPB,AQP10 |
Protein Function
AQP6 has several biochemical functions, for example, anion channel activity,glycerol channel activity,nitrate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AQP6 itself. We selected most functions AQP6 had, and list some proteins which have the same functions with AQP6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| anion channel activity | CCT8L2 |
| water channel activity | AQP8,AQP10,AQP3B,AQP10B,AQP10A,AQP3,AQP1A.2,AQP3A,AQP8A.1,AQP5 |
| glycerol channel activity | AQP9B,AQP8A.2,AQP3,MIP,AQP4,MIPA,AQP10A,AQP2,AQP7,AQP1 |
Interacting Protein
AQP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AQP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of AQP6.
Resources
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References
- Ishiyama, G; Lopez, IA; et al. Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere's disease and acoustic neuroma. CELL AND TISSUE RESEARCH 340:407-419(2010).
- Matsuki-Fukushima, M; Hashimoto, S; et al. Presence and localization of aquaporin-6 in rat parotid acinar cells. CELL AND TISSUE RESEARCH 332:73-80(2008).
