APOL3
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Official Full Name
apolipoprotein L, 3 -
Overview
This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 6. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants. -
Synonyms
APOL3;apolipoprotein L, 3;apolipoprotein L3;APOLIII;CG12 1;ApoL III;Apolipoprotein L 3;Apolipoprotein L III;Apolipoprotein LIII;TNF inducible protein CG12 1;CG12_1;apoL-III;OTTHUMP00000198071;OTTHUMP00000198072;OTTHUMP00000198073;apolipoprotein L-III;TNF-inducible protein CG12-1;CG121
Recombinant Proteins
- Human
- E.coli
- E.Coli or Yeast
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- Mammalian cells
- HEK293T
- His
- GST
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
- His&GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| APOL3-3731H | Recombinant Human APOL3 protein, His-tagged | E.coli | Human | His | 246-380 aa | |
| APOL3-3576H | Recombinant Human APOL3, His-tagged | E.Coli or Yeast | Human | His | 402 |
|
| APOL3-713H | Recombinant Human APOL3 protein, GST-tagged | Wheat Germ | Human | GST |
|
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| APOL3-8776HCL | Recombinant Human APOL3 293 Cell Lysate | HEK293 | Human | Non |
|
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| APOL3-1332HF | Recombinant Full Length Human APOL3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 331 amino acids |
|
| APOL3-1778HFL | Recombinant Full Length Human APOL3 Protein, C-Flag-tagged | Mammalian cells | Human | Flag | Full L. |
|
| APOL3-366H | Recombinant Human APOL3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| APOL3-366H-B | Recombinant Human APOL3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| APOL3-472H | Recombinant Human APOL3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| APOL3-750HFL | Recombinant Full Length Human APOL3 Protein, N-GST/C-His-tagged | E.coli | Human | His&GST | Full L. |
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Involved Pathway
APOL3 involved in several pathways and played different roles in them. We selected most pathways APOL3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APOL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APOL3 has several biochemical functions, for example, lipid binding,lipid transporter activity,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APOL3 itself. We selected most functions APOL3 had, and list some proteins which have the same functions with APOL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| signal transducer activity | VMN1R41,OLFCG3,HTR1AB,PLCH1,RGS6,GNA13A,OLFR498,OLFR478,CBLC,MUL1 |
| lipid binding | NME4,OSBPL6,PLTP,ACBD4,APOEA,SNX10B,BPIFB4,PPP5C,CYP21A1,PAQR7B |
| lipid transporter activity | APOBB.1,APOD,VTG5,APOA4,APOA1A,APOA2,MTP,VTG2,MTTP,VTG1 |
Interacting Protein
APOL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of APOL3.
bdlf2_ebvb9;purCD;dnaG;q81ye8_bacan
Resources
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References
- Chunta, S; Suk-Anake, J; et al. A piezoelectric-based immunosensor for high density lipoprotein particle measurement. ANALYST 139:4586-4592(2014).
- Xu, YN; Liu, Q; et al. Rutaecarpine suppresses atherosclerosis in ApoE(-/-) mice through upregulating ABCA1 and SR-BI within RCT. JOURNAL OF LIPID RESEARCH 55:1634-1647(2014).
