APOBEC3F
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Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F -
Overview
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
APOBEC3F;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F;DNA dC->dU-editing enzyme APOBEC-3F;ARP8;BK150C2.4.MRNA;KA6;Apolipoprotein B mRNA editing enzyme, catalytic polypeptide like 3F;Induced upon T cell activation;OTTHUMP00000199082;OTTHUMP00000199083;induced upon T-cell activation;apolipoprotein B mRNA editing enzyme cytidine deaminase;apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- Non
- His
- GST
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| APOBEC3F-1575H | Recombinant Human APOBEC3F protein | E.coli | Human | Non |
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| APOBEC3F-364R | Recombinant Rhesus monkey APOBEC3F Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| APOBEC3F-700H | Recombinant Human APOBEC3F protein, GST-tagged | Wheat Germ | Human | GST |
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| APOBEC3F-8785HCL | Recombinant Human APOBEC3F 293 Cell Lysate | HEK293 | Human | Non |
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| APOBEC3F-1411HF | Recombinant Full Length Human APOBEC3F Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 101 amino acids |
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| APOBEC3F-147H | Recombinant Human APOBEC3F Protein, His-tagged | E.coli | Human | His |
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| APOBEC3F-193R | Recombinant Rhesus Macaque APOBEC3F Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| APOBEC3F-193R-B | Recombinant Rhesus Macaque APOBEC3F Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| APOBEC3F-4426H | Recombinant Human APOBEC3F Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
APOBEC3F involved in several pathways and played different roles in them. We selected most pathways APOBEC3F participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APOBEC3F were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
APOBEC3F has several biochemical functions, for example, RNA binding,cytidine deaminase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APOBEC3F itself. We selected most functions APOBEC3F had, and list some proteins which have the same functions with APOBEC3F. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | ZNF184,HERC2,NR5A1B,CSRP1A,MORC2,GFI1,XRN2,VDRB,MT1E,UMPS |
| protein binding | AP5Z1,GFI1,ANAPC4,ZFYVE9,STK38L,CHD2,FAP,HMGCR,UHRF1,EIF2AK2 |
| cytidine deaminase activity | APOBEC2,WBP2NL,APOBEC1,AICDA,APOBEC3H,CDA,APOBEC3G |
| poly(A) RNA binding | FAM98A,MRPL14,ZNFX1,DZIP3,RPS21,EIF2S2,MTHFSD,SAMD4B,DHX37,SREK1 |
| RNA binding | EIF1AXA,TTC6,NUFIP2,PUS3,PUF60B,CELF6,PTBP1A,SMARCE1,CELF5,A1CF |
Interacting Protein
APOBEC3F has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOBEC3F here. Most of them are supplied by our site. Hope this information will be useful for your research of APOBEC3F.
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References
- Tasker, C; Ding, J; et al. 17 beta-Estradiol Protects Primary Macrophages Against HIV Infection Through Induction of Interferon-Alpha. VIRAL IMMUNOLOGY 27:140-150(2014).
- Hosseini, I; Mac Gabhann, F; et al. Multi-Scale Modeling of HIV Infection in vitro and APOBEC3G-Based Anti-Retroviral Therapy. PLOS COMPUTATIONAL BIOLOGY 8:-(2012).
