APBA2
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Official Full Name
amyloid beta (A4) precursor protein-binding, family A, member 2 -
Overview
Amyloid beta A4 precursor protein-binding family A member 2 (APBA2) is a neuronal adaptor protein that interacts with the amyloid beta precursor protein (APP). The amyloid beta-protein (Abeta), is the principal component of amyloid plaques, a pathological -
Synonyms
APBA2;amyloid beta (A4) precursor protein-binding, family A, member 2;amyloid beta (A4) precursor protein binding, family A, member 2 (X11 like) , MINT2, X11 like , X11L;amyloid beta A4 precursor protein-binding family A member 2;D15S1518E;HsT16821
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- Mammalian cell
- GST
- His
- His&T7
- Non
- His&Myc
- His&Fc&Avi
Involved Pathway
APBA2 involved in several pathways and played different roles in them. We selected most pathways APBA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APBA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APBA2 has several biochemical functions, for example, beta-amyloid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APBA2 itself. We selected most functions APBA2 had, and list some proteins which have the same functions with APBA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-amyloid binding | TGFB2,HSD17B10,BACE1,TSSK1B,APBB1,Apba1,APOA1,TM2D1,IDE,GPRASP2 |
| protein binding | ATPAF2,ZFAND5,IFNA4,HEMK1,SRGAP2,MSX2,CTBP1,RAB26,CCT8,CSNK1D |
Interacting Protein
APBA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APBA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of APBA2.
CLSTN1;USP20;App;yscK;MAPK6
Resources
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References
- Nensa, FM; Neumann, MHD; et al. Amyloid Beta A4 Precursor Protein-binding Family B Member 1 (FE65) Interactomics Revealed Synaptic Vesicle Glycoprotein 2A (SV2A) and Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2 (SERCA2) as New Binding Proteins in the Human Brain. MOLECULAR & CELLULAR PROTEOMICS 13:475-488(2014).
- Hao, Y; Chai, KH; et al. Promoter characterization and genomic organization of the human X11 beta gene APBA2. NEUROREPORT 23:146-151(2012).
