AMT
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Official Full Name
aminomethyltransferase -
Overview
This gene encodes one of four critical components of the glycine cleavage system. Mutations in this gene have been associated with glycine encephalopathy. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
AMT;aminomethyltransferase;aminomethyltransferase (glycine cleavage system protein T);aminomethyltransferase, mitochondrial;GCST;glycine cleavage system protein T;NKH;GCE;GCVT;glycine cleavage system T protein
Recombinant Proteins
- Human
- Zebrafish
- Cynomolgus
- Rhesus macaque
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- E. coli
- In Vitro Cell Free System
- HEK293
- HEK293T
- His
- GST
- Non
- N-GST
- His&Fc&Avi
- Myc&DDK
Involved Pathway
AMT involved in several pathways and played different roles in them. We selected most pathways AMT participated on our site, such as Glycine, serine and threonine metabolism,Glyoxylate and dicarboxylate metabolism,One carbon pool by folate, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glyoxylate and dicarboxylate metabolism | SHMT2,MDH2,HAO2,MDH1,GCSHA,PCCA,ANI_1_2390104,AFMID,GRHPRB,PGP |
| Glycine, serine and threonine metabolism | GAMT,GLYCTK,GRHPRB,DAO.3,GCAT,ALAS2,CBS,THA1,AGXTA,DAO |
| One carbon pool by folate | MTHFD2L,MTHFD1L,MTHFS,MTHFR,SHMT1,MTHFD2,MTHFD1,FTCD,ATIC,TYMS |
| Carbon metabolism | PGK1,HAO2,DLAT,ackA,SHMT1,GPIB,PFKP,FBP1B,TKT,OGDH |
| Metabolic pathways | POLR2G,ATP6V0CA,PDHA1B,TYMP,HPDA,AMY2A,MCAT,ATP6V0A2,IDS,NDUFA1 |
Protein Function
AMT has several biochemical functions, for example, aminomethyltransferase activity,transaminase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AMT itself. We selected most functions AMT had, and list some proteins which have the same functions with AMT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transaminase activity | AGXT2L2,AGXT2L1,AGXT,ETNPPL,GOT2B,GOT2A,AGXTB,PHYKPL,AGXT2,CCBL1 |
| aminomethyltransferase activity | GCSH |
Interacting Protein
AMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMT here. Most of them are supplied by our site. Hope this information will be useful for your research of AMT.
q96be0_human
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References
- Hashemi, M; Taherimaslak, Z; et al. Application of magnetic solid phase extraction for separation and determination of aflatoxins B-1 and B-2 in cereal products by high performance liquid chromatography-fluorescence detection. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 960:200-208(2014).
- Yoon, JY; Ishdorj, G; et al. Valproic acid enhances fludarabine-induced apoptosis mediated by ROS and involving decreased AKT and ATM activation in B-cell-lymphoid neoplastic cells. APOPTOSIS 19:191-200(2014).
