ALX3
-
Official Full Name
ALX homeobox 3 -
Overview
This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this genes promoter is associated with advanced-stage neuroblastoma tumors. -
Synonyms
ALX3;ALX homeobox 3;aristaless like homeobox 3;homeobox protein aristaless-like 3;ALX 3;Homeobox protein aristaless like 3;MGC138212;MGC141988;Proline rich transcription factor ALX3;OTTHUMP00000013372;aristaless-like homeobox 3;proline-rich transcription factor ALX3;FND1
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- Wheat Germ
- HEK293T
- HEK293
- E.coli
- His
- GST
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ALX3-1582M | Recombinant Mouse ALX3 Protein | Mammalian Cell | Mouse | His |
|
|
| ALX3-510H | Recombinant Human ALX3 protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| ALX3-1368H | Recombinant Human ALX3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
|
| ALX3-1991H | Recombinant Human ALX3 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
|
|
| ALX3-495M | Recombinant Mouse ALX3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| ALX3-495M-B | Recombinant Mouse ALX3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| ALX3-511H | Recombinant Human ALX3 protein, GST-tagged | E.coli | Human | GST | 1-152 aa |
|
| Alx3-589M | Recombinant Mouse Alx3 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
Involved Pathway
ALX3 involved in several pathways and played different roles in them. We selected most pathways ALX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ALX3 has several biochemical functions, for example, DNA binding,sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALX3 itself. We selected most functions ALX3 had, and list some proteins which have the same functions with ALX3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZSCAN18,PURBA,ORC1L,ISL2A,PDCD2,HIF1AL2,CENPA,RARB,NTNG1,LTF |
| sequence-specific DNA binding | AHR,CLOCK,HOXB8A,USF1,FOXH1,ZFP536,TCF3A,NR4A1,ENG2A,BCL11AA |
| transcription factor activity, sequence-specific DNA binding | RORB,KLF10,IRF2,ARNTL2,SRF,MEF2D,HIVEP2A,SOX5,ZNF643,ZNF613 |
Interacting Protein
ALX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALX3.
Resources
Related Services
Related Products
References
- Fernandez-Perez, A; Vallejo, M; et al. Pdx1 and USF transcription factors co-ordinately regulate Alx3 gene expression in pancreatic beta-cells. BIOCHEMICAL JOURNAL 463:287-296(2014).
- Liu, WB; Han, F; et al. Epigenetic silencing of Aristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer. INTERNATIONAL JOURNAL OF CANCER 134:1311-1322(2014).
