Alox12

  • Official Full Name

    arachidonate 12-lipoxygenase

  • Overview

    Arachidonate 12-lipoxygenase, 12S-type is an enzyme that in humans is encoded by the ALOX12 gene.

  • Synonyms

    ALOX12;arachidonate 12-lipoxygenase;arachidonate 12-lipoxygenase, 12S-type;12S-type;12 Lox;12(S) lipoxygenase;12S LOX;12S-lipoxygenase;12S-LOX;Alox 12;Alox12L;Alox15;Arachidonate 12 lipoxygenase 12S type;Arachidonate 12 lipoxygenase;Arachidonate 12 lipoxygenase leukocyte type;Arachidonate 12 lipoxygenase, 12S type;Arachidonate 12 lipoxygenase, leukocyte type;EC1.13.11.31;LOG 12;LOG12;LOX12_HUMAN;Platelet type 12 lipoxygenase;Platelet type lipoxygenase 12;Platelet-type lipoxygenase 12;P-12LO;Alox12p;9930022G08Rik

Recombinant Proteins

  • Human
  • Zebrafish
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • Insect Cells
  • In Vitro Cell Free System
  • HEK293
  • Non
  • His
  • T7
  • GST
  • Flag
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
ALOX12-01H Recombinant Human ALOX12 Protein E.coli Human Non
ALOX12-2815H Recombinant Human ALOX12 protein, His-tagged E.coli Human His 111 - 230 aa
ALOX12-10019Z Recombinant Zebrafish ALOX12 Mammalian Cells Zebrafish His
ALOX12-2031H Recombinant Human ALOX12 protein, His & T7-tagged E.coli Human His&T7 Phe352~Cys656
ALOX12-269H Recombinant Human ALOX12 Mammalian Cells Human His
ALOX12-482H Recombinant Human ALOX12 Protein, GST-tagged Wheat Germ Human GST
Alox12-584M Recombinant Mouse Arachidonate 12-lipoxygenase, His-tagged Insect Cells Mouse His
ALOX12-64HCL Recombinant Human ALOX12 cell lysate Human Non
Alox12-021M Recombinant mouse Alox12 Protein, His-tagged Insect Cells Mouse His 2-664
ALOX12-0560H Recombinant Human ALOX12 Protein (Phe352-Cys656), N-His-tagged E.coli Human His Phe352-Cys656
Alox12-104M Recombinant Mouse Alox12 Protein, His-tagged Insect Cells Mouse His
ALOX12-1466HF Recombinant Full Length Human ALOX12 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 663 amino acids
ALOX12-1478HFL Recombinant Full Length Human ALOX12 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
ALOX12-18HF Recombinant Full Length Human ALOX12 Protein In Vitro Cell Free System Human Full L. 663 amino acids
ALOX12-2197H Recombinant Human ALOX12 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
ALOX12-2510H Recombinant Human ALOX12 protein, His-tagged E.coli Human His 1-663aa
ALOX12-26002TH Recombinant Human ALOX12 Wheat Germ Human Non 663 amino acids
ALOX12-323H Recombinant Human ALOX12 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
ALOX12-323H-B Recombinant Human ALOX12 Protein Pre-coupled Magnetic Beads HEK293 Human
Alox12-578M Recombinant Mouse Alox12 Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    Alox12 involved in several pathways and played different roles in them. We selected most pathways Alox12 participated on our site, such as Arachidonic acid metabolism,Metabolic pathways,Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Alox12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism CYP2P7,PLA2G16,FAAH2B,CYP1B1,AWAT1,ALOX12B,CBR1,GPX2,GGTLC1,PLA2G5
    Serotonergic synapse HTR5A,HTR3A,HTR4,MAPK1,ALOX15B,KRAS,CYP2C55,GNAQ,CYP2C38,GNB1
    Metabolic pathways GMPPA,PIP5K1BB,TPH1,ALOX12E,P4HA1A,PYCRL,CMPK1,GNE,HMBSB,UCK2
    Inflammatory mediator regulation of TRP channels ASIC4,NTRK1,PRKCB,MAP2K3,IL1B,PIK3CD,PLCB1,PIK3CA,ACCN3,MAPK10

    Protein Function

    Alox12 has several biochemical functions, for example, arachidonate 12-lipoxygenase activity,hepoxilin A3 synthase activity,hepoxilin-epoxide hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Alox12 itself. We selected most functions Alox12 had, and list some proteins which have the same functions with Alox12. You can find most of the proteins on our site.

    Function Related Protein
    oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen BCO2,ALOX12E,TMLHE,ALOX12B,P4HA1,ADOA,ALOX5A,P4HA1B,P4HA3,ALOX5B.2
    hepoxilin A3 synthase activity ALOX15
    linoleate 13S-lipoxygenase activity ALOX8,ALOX15B
    hepoxilin-epoxide hydrolase activity ALOX15
    protein binding SNX10,FBXO32,KIF6,GFER,USP20,TTC25,MYL7,AGR2,TTBK2,AMY1A
    iron ion binding CYP2AA2,PHF8,CYP2F2,BA1,CYP4A12A,CYP3C1,P4HTM,CYP3A43,P3H2,CYP11C1
    arachidonate 12-lipoxygenase activity ALOX12B,ALOX12E,ALOX15

    Interacting Protein

    Alox12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Alox12 here. Most of them are supplied by our site. Hope this information will be useful for your research of Alox12.

    KRT5;LMNA;PLA2G2A;ITGB4;TRIB1

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