ALG6

  • Official Full Name

    asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)

  • Overview

    This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the first glucose residue to the growing lipid-linked oligosaccharide precursor of N-linked glycosylation. Mutations in this gene are associated with congenital disorders of glycosylation type Ic.

  • Synonyms

    ALG6;asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae);asparagine linked glycosylation 6 homolog (yeast, alpha 1,3 glucosyltransferase);dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase;E230028F23Rik;Asparagine linked glycosylation 6;Asparagine linked glycosylation 6 homolog (S. cerevisiae alpha 1 3 glucosyltransferase);Asparagine linked glycosylation 6 homolog;Dolichyl P Glc:Man9GlcNAc2 PP dolichyl glucosyltransferase;Dolichyl P Glc:Man9GlcNAc2 PP dolichylglucosyltransferase;Dolichyl pyrophosphate Man9GlcNAc2 alpha 1 3 glucosyltransferase;Man(9)GlcNAc(2) PP Dol alpha 1 3 glucosyltransferase;MGC124652;My 046;My046;OTTMUSP00000008309;RP23-35D18.4;asparagine-linked glycosylation protein 6 homolog;Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase;dolichyl-P-Glc:Man9GlcNAc2-PP-dolichylglucosyltransferase;dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase;dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase;asparagine-linked glycosylation 6 homolog (yeast, alpha-1,3-glucosyltransferase);asparagine-linked glycosylation 6 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase);CDG1C

Recombinant Proteins

  • Zebrafish
  • Mouse
  • Human
  • Chicken
  • Rat
  • Mammalian Cells
  • Wheat Germ
  • E.coli
  • HEK293
  • His
  • GST
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
ALG6-1117Z Recombinant Zebrafish ALG6 Mammalian Cells Zebrafish His
ALG6-1549M Recombinant Mouse ALG6 Protein Mammalian Cells Mouse His
ALG6-466H Recombinant Human ALG6 Protein, GST-tagged Wheat Germ Human GST
ALG6-6005C Recombinant Chicken ALG6 Mammalian Cells Chicken His
ALG6-630R Recombinant Rat ALG6 Protein Mammalian Cells Rat His
ADAM10-2422H Recombinant Human ADAM10 protein, GST-tagged E.coli Human GST 306-512 aa
ALG6-286R Recombinant Rat ALG6 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
ALG6-286R-B Recombinant Rat ALG6 Protein Pre-coupled Magnetic Beads HEK293 Rat
ALG6-469M Recombinant Mouse ALG6 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ALG6-469M-B Recombinant Mouse ALG6 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ALG6 involved in several pathways and played different roles in them. We selected most pathways ALG6 participated on our site, such as N-Glycan biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALG6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways SCP2,GAL3ST1A,CBSB,PANK4,NME2B.2,PAFAH1B2,ADSL,ATP5C1,ME1,AK8
    N-Glycan biosynthesis ALG8,FUT8,MGAT3A,B4GALT2,GANAB,MGAT4C,ALG14,ALG11,FUT8A,ALG9

    Protein Function

    ALG6 has several biochemical functions, for example, dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity,glucosyltransferase activity,transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALG6 itself. We selected most functions ALG6 had, and list some proteins which have the same functions with ALG6. You can find most of the proteins on our site.

    Function Related Protein
    transferase activity, transferring glycosyl groups PIGB,C1GALT1B,B3GNT5A,HAS2,UGT1B5,LARGE,UGT2A4,EXT1A,A3GALT2,PNP5A
    transferase activity PKM,UGT2A6,NADKD1,EPHA2A,ADKB,MAPK8B,DYRK1AA,PRKACAA,RAF1B,SULT1D1
    dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity GALNTL4,POC1BL,B3GNT8,ALG8,GALNT18A,4931440L10Rik,DPY19L1,GTDC2,DPY19L4,B3GNTL1
    glucosyltransferase activity B3GNTL1,GALNT18A,KDELC2,4931440L10Rik,POGLUT1,GALNTL4,POMGNT2,GTDC2,DPY19L1,B3GNT8
    transferase activity, transferring hexosyl groups GGTA1,UGT1AB,UGT2A6,UGT1A5,UGT5A1,UGT5G2,B4GALNT1A,UGT1B3,UGT2A5,UGT2B1

    Interacting Protein

    ALG6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALG6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALG6.

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