ALG6
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Official Full Name
asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae) -
Overview
This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the first glucose residue to the growing lipid-linked oligosaccharide precursor of N-linked glycosylation. Mutations in this gene are associated with congenital disorders of glycosylation type Ic. -
Synonyms
ALG6;asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae);asparagine linked glycosylation 6 homolog (yeast, alpha 1,3 glucosyltransferase);dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase;E230028F23Rik;Asparagine linked glycosylation 6;Asparagine linked glycosylation 6 homolog (S. cerevisiae alpha 1 3 glucosyltransferase);Asparagine linked glycosylation 6 homolog;Dolichyl P Glc:Man9GlcNAc2 PP dolichyl glucosyltransferase;Dolichyl P Glc:Man9GlcNAc2 PP dolichylglucosyltransferase;Dolichyl pyrophosphate Man9GlcNAc2 alpha 1 3 glucosyltransferase;Man(9)GlcNAc(2) PP Dol alpha 1 3 glucosyltransferase;MGC124652;My 046;My046;OTTMUSP00000008309;RP23-35D18.4;asparagine-linked glycosylation protein 6 homolog;Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase;dolichyl-P-Glc:Man9GlcNAc2-PP-dolichylglucosyltransferase;dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase;dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase;asparagine-linked glycosylation 6 homolog (yeast, alpha-1,3-glucosyltransferase);asparagine-linked glycosylation 6 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase);CDG1C
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Chicken
- Rat
- Mammalian Cell
- Wheat Germ
- E. coli
- HEK293
- His
- GST
- N-GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ALG6-1117Z | Recombinant Zebrafish ALG6 | Mammalian Cell | Zebrafish | His |
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| ALG6-1549M | Recombinant Mouse ALG6 Protein | Mammalian Cell | Mouse | His |
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| ALG6-466H | Recombinant Human ALG6 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ALG6-6005C | Recombinant Chicken ALG6 | Mammalian Cell | Chicken | His |
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| ALG6-630R | Recombinant Rat ALG6 Protein | Mammalian Cell | Rat | His |
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| ADAM10-2422H | Recombinant Human ADAM10 protein, GST-tagged | E. coli | Human | N-GST | 306-512 aa |
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| ALG6-286R | Recombinant Rat ALG6 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ALG6-286R-B | Recombinant Rat ALG6 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ALG6-469M | Recombinant Mouse ALG6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ALG6-469M-B | Recombinant Mouse ALG6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ALG6 involved in several pathways and played different roles in them. We selected most pathways ALG6 participated on our site, such as N-Glycan biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALG6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | B3GNT5,FAH,Cel,GALCB,PIGL,CYP2C37,DAO.1,DEGS2,PGAM1A,CERS1 |
| N-Glycan biosynthesis | B4GALT3,MAN2A2,MGAT1,MGAT5B,MGAT4A,ALG5,ALG12,MGAT2,ST6GAL2A,RPN2 |
Protein Function
ALG6 has several biochemical functions, for example, dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity,glucosyltransferase activity,transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALG6 itself. We selected most functions ALG6 had, and list some proteins which have the same functions with ALG6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transferase activity, transferring glycosyl groups | UGT5A5,UGGT1,FUT9B,MGAT4C,C1GALT1A,GLT25D2,UGT2B5,UGT5A3,B3GALTLB,PNP4A |
| transferase activity | NDUFAF5,PHKG1A,ZDHHC18A,WBP7,CDK14,TNIKA,BMPR2A,CAMK1GB,GSBP9,UGT5C2 |
| dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity | POC1BL,GALNTL4,B3GNTL1,DPY19L4,DPY19L1,B3GNT9-PS,GALNT18A,4931440L10Rik,PIGB,POMGNT2 |
| glucosyltransferase activity | KDELC2,POGLUT1,B3GNTL1,DPY19L1,GLT8D1,4931440L10Rik,GALNTL4,GALNT18A,GTDC2,POMGNT2 |
| transferase activity, transferring hexosyl groups | UGT5A3,UGT5D1,UGT5B6,UGT2A6,UGT2B1,GGTA1,UGT2A5,UGT5C3,UGT2B3,GBGT1 |
Interacting Protein
ALG6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALG6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALG6.
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