ALG13
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Official Full Name
asparagine-linked glycosylation 13 homolog (S. cerevisiae) -
Overview
The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ALG13;asparagine-linked glycosylation 13 homolog (S. cerevisiae);chromosome X open reading frame 45 , CXorf45, GLT28D1, glycosyltransferase 28 domain containing 1;UDP-N-acetylglucosamine transferase subunit ALG13 homolog;FLJ23018;MDS031;YGL047W;Glycosyltransferase 28 domain containing protein 1;UDP N acetylglucosamine transferase subunit ALG13 homolog;glycosyltransferase 28 domain containing 1;glycosyltransferase 28 domain-containing protein 1;hematopoietic stem/progenitor cells protein MDS031;CXorf45;GLT28D1
Recombinant Proteins
- Mouse
- Zebrafish
- Rat
- Human
- Mammalian Cell
- HEK293
- E. coli
- E.coli
- His
- Non
- N-His
- His&Fc&Avi
- GST
Involved Pathway
ALG13 involved in several pathways and played different roles in them. We selected most pathways ALG13 participated on our site, such as N-Glycan biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALG13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| N-Glycan biosynthesis | DPAGT1,ST6GAL2A,MGAT4B,DPM3,ALG3,MGAT4C,ALG12,RABGNT1,B4GALT2,STT3B |
| Metabolic pathways | NOS1,EXT1C,RPN2,CES1,FBP1A,BHMT,MVDA,R05D11.9,CYP2C45,ALDH9A1B |
Protein Function
ALG13 has several biochemical functions, for example, N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity,cysteine-type peptidase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALG13 itself. We selected most functions ALG13 had, and list some proteins which have the same functions with ALG13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type peptidase activity | CTSJ,CASP8,CTSLL,OTUD7B,CASP6L1,CASP3A,UFSP2,USP43A,SENP3A,CTS7 |
| poly(A) RNA binding | HELZ2,MRPS30,ANXA11,PSMD4,UBAP2,RPL37A,NOP56,TIA1,IGF2BP1,RPL3 |
| protein binding | RPS18,TMUB2,CDK5RAP3,TPD52L3,TRIM42,SIRT3,HIST1H3G,EPM2A,TTC30B,Clec4n |
Interacting Protein
ALG13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALG13 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALG13.
ATN1;mscS2;RERE;q9wmx2-pro_0000037548;SAV1
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References
- Michaud, JL; Lachance, M; et al. The genetic landscape of infantile spasms. HUMAN MOLECULAR GENETICS 23:4846-4858(2014).
- De Antonellis, P; Carotenuto, M; et al. Early Targets of miR-34a in Neuroblastoma. MOLECULAR & CELLULAR PROTEOMICS 13:2114-2131(2014).
